ArticleJournal of biomechanics2018
Modifying hernia mesh design to improve device mechanical performance and promote tension-free repair.
Article in Journal of biomechanics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
What it found
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Who cites it
13 citing papers in PubMed, 21 citations in OpenAlex.
- Mechanical biocompatibility of synthetic meshes in incisional hernia repair: insights from a clinical dataset.Journal of medicine and life · 2026Article
- Multimodal Prehabilitation for Hernia Repair: Linking Metabolic Modulation and Mechanical Methods.Biomedicines · 2025Review
- Innovative Strategies in Hernia Mesh Design: Materials, Mechanics, and Modeling.Materials (Basel, Switzerland) · 2025Review
- CORR Insights®: Synthetic Mesh Reconstruction Improves Pelvic Floor Function and Quality of Life After Sacrectomy: A Preliminary Clinical Assessment.Clinical orthopaedics and related research · 2025Article
- Ventral hernia repair with T-line hernia mesh: A multi-institutional experience.Surgery in practice and science · 2025Article
- A mouse model of volumetric muscle loss and therapeutic scaffold implantation.Nature protocols · 2025Review
- Retrorectus Ventral Hernia Repair Utilizing T-line Hernia Mesh: Technical Descriptions.Plastic and reconstructive surgery. Global open · 2024Article
- T-line Hernia Mesh Repairs of Large Umbilical Hernias: Technique and Short-term Outcomes.Plastic and reconstructive surgery. Global open · 2024Article
- Abdominal wall hernia repair: from prosthetic meshes to smart materials.Materials today. Bio · 2023Review
- Evolving concepts in ventral hernia repair and physical therapy: prehabilitation, rehabilitation, and analogies to tendon reconstruction.Hernia : the journal of hernias and abdominal wall surgery · 2021Review
- Regulatory science for hernia mesh: Current status and future perspectives.Bioactive materials · 2021Review
- Anti-inflammatory coating of hernia repair meshes: a 5-rabbit study.Hernia : the journal of hernias and abdominal wall surgery · 2020Article
- Soft Tissue Anchoring Performance, Biomechanical Properties, and Tissue Reaction of a New Hernia Mesh Engineered to Address Hernia Occurrence and Recurrence.Journal of medical devices · 2019Article
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
Abstract
purposeApproximately 348,000 ventral hernia repairs are performed annually in the United States and the incisional hernia recurrence rate is approximately 20% as a result of suture and mesh device failure. Device failure is related to changes at the suture/tissue interface that leads to acute or chronic suture pull-through and surgical failure. To better manage mechanical tension, we propose a modified mesh design with extensions and demonstrate its mechanical superiority.
methodsComparative uniaxial static tensile testing was conducted on polypropylene suture and a modified mesh. Subsequently, a standard of care (SOC) mesh and modified mesh were evaluated using a tensometer in an acute hernia bench-top model.
resultsModified mesh breaking strength, extension knot breaking strength, extension disruption, and extension anchoring were superior to suture (p < .05). Modified mesh ultimate tensile strength of anchoring was superior to SOC mesh (p < .05). Various stitch patterns and modifications in device design significantly improved device tension-free performance far beyond clinically relevant benchmarks (p < .05).
conclusionsTesting demonstrates that the modified mesh outperforms SOC mesh and suture in all tested failure modes. SOC hernia mesh tears through tissue at stress levels below maximum physiologic stress, whereas, the modified hernia mesh is up to 200% stronger than SOC mesh at resisting suture tearing through tissue and maintains anchoring at stresses far beyond clinically relevant benchmarks. Modifying hernia mesh design significantly improves device mechanical performance and enhances tension-free repair.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.