ArticleThe American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry2018
Symptomatic and Functional Recovery From Major Depressive Disorder in the Ibadan Study of Ageing.
Article in The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed.
- A longitudinal analysis of the relationship between emotional symptoms and cognitive function in patients with major depressive disorder.Psychological medicine · 2025Article
- Longitudinal Studies of Aging in Sub-Saharan Africa: Review, Limitations, and Recommendations in Preparation of Projected Aging Population.Innovation in aging · 2024Review
- Article
- Late-life depression in sub-Saharan Africa: lessons from the Ibadan Study of Ageing.Epidemiology and psychiatric sciences · 2020Article
- Trajectories of major depression in middle-aged and older adults: A population-based study.International journal of geriatric psychiatry · 2019Article
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4 authors.
Funding
Abstract
objectivesVery little is known about the association between symptomatic and functional recovery from late-life major depressive disorder (MDD) in sub-Saharan Africa. We investigated factors associated with sustained symptomatic remission (SR) from MDD and the 5-year trajectory of post-MDD physical functioning.
design5-year prospective study with three follow-up waves in 2007, 2008, and 2009. SETTING/
participantsHousehold multistage probability sample of 2,149 Nigerians who were aged 65 years or older. MEASUREMENTS: Activities of Daily Living (ADL) and MDD were assessed using the Kadz index and Composite International Diagnostic Interview, respectively. We studied those with current MDD (prevalent in 2003-2004 or incident in 2007), and who achieved SR in subsequent waves compared with a chronic/recurrent course (CR).
resultsBaseline demographic characteristics, health, and lifestyle factors were not associated with SR in logistic regression analyses. In mixed-effect linear regression models adjusting for age, sex, and socioeconomic status, ADL worsened in SR (β = 1.0, 95% CI: 0.2, 1.8), but more so in CR (β = 2.3, 95% CI: 1.6, 3.0). Poorer ADL at follow-up was predicted by age (β = 2.9, 95% CI: 1.8, 4.0) and economic status (β = 1.4, 95% CI: 0.3, 2.4).
conclusionsThere was a deteriorating course of disability despite symptomatic recovery from late-life MDD in this sample. This finding has implications for policy and guidelines for the management of late-life depression and disability.
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