Evidence map›Paper›PMID 29426291›Full record

SynthesisBMC pediatrics2018

Paediatric pancreaticobiliary endoscopy: a 21-year experience from a tertiary hepatobiliary centre and systematic literature review.

Margaret G Keane, Mayur Kumar, Natascha Cieplik, Douglas Thorburn, Gavin J Johnson, George J Webster, Michael H Chapman, Keith J Lindley, Stephen P Pereira

Open access · goldAbstract readSystematic Review
In one paragraph

Synthesis in BMC pediatrics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
1.7field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 35 citations in OpenAlex.

  1. Article
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  5. Review
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  7. Safety and efficacy of endoscopic retrograde cholangiopancreatography in pediatric pancreatic and biliary disorders.Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2024
    Article
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  11. Review
  12. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Margaret G KeaneInstitute for Liver and Digestive Health, University College London, Royal Free Campus, Pond St, London, NW3 2PF, UK.
Mayur KumarDepartment of Gastroenterology, University College of London Hospital, 235 Euston Road, London, NW1 2BG, UK.
Natascha CieplikInstitute for Liver and Digestive Health, University College London, Royal Free Campus, Pond St, London, NW3 2PF, UK.
Douglas ThorburnInstitute for Liver and Digestive Health, University College London, Royal Free Campus, Pond St, London, NW3 2PF, UK.
Gavin J JohnsonDepartment of Gastroenterology, University College of London Hospital, 235 Euston Road, London, NW1 2BG, UK.
George J WebsterDepartment of Gastroenterology, University College of London Hospital, 235 Euston Road, London, NW1 2BG, UK.
Michael H ChapmanDepartment of Gastroenterology, University College of London Hospital, 235 Euston Road, London, NW1 2BG, UK.
Keith J LindleyDepartment of Gastroenterology, Great Ormond Street Hospital, London, WC1N 3JN, UK.
Stephen P PereiraInstitute for Liver and Digestive Health, University College London, Royal Free Campus, Pond St, London, NW3 2PF, UK. stephen.pereira@ucl.ac.uk.
The Royal Free Hospital · GBUniversity College London · GBUniversity College Hospital · GBGreat Ormond Street Hospital · GB

Funding

Department of Health [UK]
6 · The paper itself

Abstract

backgroundIn adults ERCP and endoscopic ultrasound (EUS) are standard methods of evaluating and treating many hepatopancreaticobiliary (HPB) conditions. HPB disease is being diagnosed with increasing frequency in children but information about role of ERCP and EUS and their outcomes in this population remain limited. Therefore the aims of this study were to describe the paediatric ERCP and EUS experience from a large tertiary referral HPB centre, and to systematically compare outcomes with those of other published series.

methodsAll patients <18 years undergoing an ERCP or EUS between January 1992-December 2014 were included. Indications for the procedure, rates of technical success, procedural adverse events and reinterventions were recorded in all cases.

resultsNinety children underwent 111 procedures (87 ERCPs and 24 EUS). 53% (48) were female with a median age of 14 years (range: 3 months - 17 years). Procedures were performed under general anaesthesia (n = 48) or conscious sedation (n = 63). Common indications for ERCP included chronic or recurrent pancreatitis and biliary obstruction. Patients frequently had multiple comorbidities, with a median ASA grade of 2 (range 1-4). Therapeutic procedures performed included biliary or pancreatic sphincterotomy, common bile duct or pancreatic duct stone removal, biliary or pancreatic stent insertion, EUS-guided fine needle aspiration and endoscopic transmural drainage of pancreatic fluid collections. No adverse events were reported following ERCP but there was one complication requiring surgery following EUS guided cystenterostomy.

conclusionERCP and EUS in children and adolescents have high technical success rates and low rates of adverse events when performed in high volume HPB centres.

Indexed as

Biliary Tract DiseasesCholangiopancreatography, Endoscopic RetrogradeEndosonographyPancreatic DiseasesAdolescentChildChild, PreschoolFemaleFollow-Up StudiesHumansInfantMaleRetrospective StudiesTreatment OutcomeBiliary leakCholedocholithiasisChronic pancreatitisCystic lesion of the pancreasEndoscopic retrograde Cholangiopancreaticography (ERCP)Endoscopic ultrasound (EUS)PaediatricPancreatic fluid collectionPrimary sclerosing cholangitisTransmural drainage

Identifiers

PMID29426291
PMCPMC5807847
OpenAlexW2792694841

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.