ArticleBMC genomics2018
Transcriptome profiling of two maize inbreds with distinct responses to Gibberella ear rot disease to identify candidate resistance genes.
Article in BMC genomics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 1 of them a synthesis that pooled it.
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Who cites it
29 citing papers in PubMed, 1 synthesis or guideline pooled it, 62 citations in OpenAlex.
- Meta-analysis and co-expression analysis revealed stable QTL and candidate genes conferring resistances to Fusarium and Gibberella ear rots while reducing mycotoxin contamination in maize.Frontiers in plant science · 2022Pooled it
- RNA-Seq analysis reveals early defense activation and responses associated with resistance to Fusarium thapsinum stalk infection in sorghum.BMC genomics · 2026Article
- Regulatory balance between ear rot resistance and grain yield and their breeding applications in maize and other crops.Journal of advanced research · 2025Review
- TaWI12 may be involved in pistillody and leaf cracking in wheat.BMC plant biology · 2025Article
- Predictive prioritization of genes significantly associated with biotic and abiotic stresses in maize using machine learning algorithms.Frontiers in plant science · 2025Article
- Transcriptome profiling of eight Zea mays lines identifies genes responsible for the resistance to Fusarium verticillioides.BMC plant biology · 2024Article
- Cell wall-related genes and lignin accumulation contribute to the root resistance in different maize (Frontiers in plant science · 2023Article
- Comprehensive meta-analysis of QTL and gene expression studies identify candidate genes associated withFrontiers in plant science · 2023Article
- Article
- OMICS in Fodder Crops: Applications, Challenges, and Prospects.Current issues in molecular biology · 2022Review
- Network and Evolutionary Analysis Reveals Candidate Genes of Membrane Trafficking Involved in Maize Seed Development and Immune Response.Frontiers in plant science · 2022Article
- Autotoxin affects the rhizosphere microbial community structure by influencing the secretory characteristics of grapevine roots.Frontiers in microbiology · 2022Article
- Transcriptomic Analysis Reveals Candidate Genes Responding Maize Gray Leaf Spot Caused byPlants (Basel, Switzerland) · 2021Article
- Omics for the Improvement of Abiotic, Biotic, and Agronomic Traits in Major Cereal Crops: Applications, Challenges, and Prospects.Plants (Basel, Switzerland) · 2021Review
- Identification and Cloning of a CC-NBS-NBS-LRR Gene as a Candidate ofInternational journal of molecular sciences · 2021Article
- Variation in Gene Expression between TwoPlants (Basel, Switzerland) · 2021Article
- Comparative Transcriptome Analysis Reveals Regulatory Networks during the Maize Ear Shank Elongation Process.International journal of molecular sciences · 2021Article
- The eukaryotic MEP-pathway genes are evolutionarily conserved and originated from Chlaymidia and cyanobacteria.BMC genomics · 2021Article
- A temporal hierarchy underpins the transcription factor-DNA interactome of the maize UPR.The Plant journal : for cell and molecular biology · 2021Article
- Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundGibberella ear rot (GER) is one of the most economically important fungal diseases of maize in the temperate zone due to moldy grain contaminated with health threatening mycotoxins. To develop resistant genotypes and control the disease, understanding the host-pathogen interaction is essential.
resultsRNA-Seq-derived transcriptome profiles of fungal- and mock-inoculated developing kernel tissues of two maize inbred lines were used to identify differentially expressed transcripts and propose candidate genes mapping within GER resistance quantitative trait loci (QTL). A total of 1255 transcripts were significantly (P ≤ 0.05) up regulated due to fungal infection in both susceptible and resistant inbreds. A greater number of transcripts were up regulated in the former (1174) than the latter (497) and increased as the infection progressed from 1 to 2 days after inoculation. Focusing on differentially expressed genes located within QTL regions for GER resistance, we identified 81 genes involved in membrane transport, hormone regulation, cell wall modification, cell detoxification, and biosynthesis of pathogenesis related proteins and phytoalexins as candidate genes contributing to resistance. Applying droplet digital PCR, we validated the expression profiles of a subset of these candidate genes from QTL regions contributed by the resistant inbred on chromosomes 1, 2 and 9.
conclusionBy screening global gene expression profiles for differentially expressed genes mapping within resistance QTL regions, we have identified candidate genes for gibberella ear rot resistance on several maize chromosomes which could potentially lead to a better understanding of Fusarium resistance mechanisms.
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Registered trials
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