Evidence map›Paper›PMID 29426027›Full record

ArticleEnvironmental research2018

Ozone, NO

Maxime Jeanjean, Marie-Abele Bind, Jonathan Roux, Jean-Claude Ongagna, Jérôme de Sèze, Denis Bard, Emmanuelle Leray

Abstract read
In one paragraph

Article in Environmental research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Invisible symptoms and associated factors in multiple sclerosis patients.Journal of education and health promotion · 2026
    Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Effects of PMToxics · 2024
    Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Review
  14. Article
  15. Review
  16. Review
  17. Effect of polycyclic aromatic hydrocarbons on immunity.Journal of translational autoimmunity · 2022
    Article
  18. Air pollution and multiple sclerosis: a comprehensive review.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2021
    Review
  19. Impact of Climate Change on Eye Diseases and Associated Economical Costs.International journal of environmental research and public health · 2021
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Maxime JeanjeanMETIS Department, EHESP French School of Public Health, Sorbonne Paris Cité, 15 avenue du Professeur 6 Léon-Bernard - CS 74312, 35043 Rennes, France. Electronic address: maxime.jeanjean@ehesp.fr.
Marie-Abele BindDepartment of Statistics, Harvard University, Faculty of Arts and Sciences, Cambridge, MA, USA. Electronic address: ma.bind@mail.harvard.edu.
Jonathan RouxMETIS Department, EHESP French School of Public Health, Sorbonne Paris Cité, 15 avenue du Professeur 6 Léon-Bernard - CS 74312, 35043 Rennes, France; INSERM CIC-P 1414, CHU of Rennes, 2 Rue Henri le Guilloux, 35000 Rennes, France; EA 7449 REPERES, EHESP French School of Public Health, Sorbonne Paris Cité - University of Rennes 1, Rennes, France. Electronic address: jonathan.roux@ehesp.fr.
Jean-Claude OngagnaDepartment of neurology, Strasbourg University, INSERM CIC 1434, CHU of Strasbourg, 1 Place de l'Hôpital, 11 67091 Strasbourg cedex, France. Electronic address: jean-claude.ongagna@chru-strasbourg.fr.
Jérôme de SèzeDepartment of neurology, Strasbourg University, INSERM CIC 1434, CHU of Strasbourg, 1 Place de l'Hôpital, 11 67091 Strasbourg cedex, France. Electronic address: jerome.de.seze@chru-strasbourg.fr.
Denis BardMETIS Department, EHESP French School of Public Health, Sorbonne Paris Cité, 15 avenue du Professeur 6 Léon-Bernard - CS 74312, 35043 Rennes, France. Electronic address: denis.bard@ehesp.fr.
Emmanuelle LerayMETIS Department, EHESP French School of Public Health, Sorbonne Paris Cité, 15 avenue du Professeur 6 Léon-Bernard - CS 74312, 35043 Rennes, France; INSERM CIC-P 1414, CHU of Rennes, 2 Rue Henri le Guilloux, 35000 Rennes, France; EA 7449 REPERES, EHESP French School of Public Health, Sorbonne Paris Cité - University of Rennes 1, Rennes, France. Electronic address: emmanuelle.leray@ehesp.fr.

Funding

Transporting established insights from classical experimental design to address causal questions in environmental epidemiology including the understanding of biological mediating mechanismsDP5OD021412 · OD · MASSACHUSETTS GENERAL HOSPITAL · PI BIND, MARIE-ABELE CATHERINE · 2016 to 2020
$2.1M
NIH HHS DP5 OD021412
6 · The paper itself

Abstract

backgroundTriggers of multiple sclerosis (MS) relapses are essentially unknown. PM

objectivesWe further explore the short-term associations between PM

methodsUsing a case-crossover design, we studied 424 MS patients living in the Strasbourg area, France between 2000 and 2009 (1783 relapses in total). Control days were chosen to be ± 35 days relative to the case (relapse) day. Exposure was modeled through ADMS-Urban software at the census block scale. We consider single-pollutant and multi-pollutant conditional logistic regression models coupled with a distributed-lag linear structure, stratified by season ("hot" vs. "cold"), and adjusted for meteorological parameters, pollen count, influenza-like epidemics, and holidays.

resultsThe single-pollutant analyses indicated: 1) significant associations between MS relapse incidence and exposures to NO

conclusionWe observed significant single-pollution associations between the occurrence of MS relapses and exposures to NO

Indexed as

Air PollutantsAir PollutionMultiple SclerosisNitrogen DioxideOzoneParticulate MatterAdultFemaleFranceHumansMaleRecurrenceSeasonsAir PollutantsNitrogen DioxideOzoneParticulate MatterAir pollutionMultiple sclerosisRelapseSocioeconomic position

Identifiers

PMID29426027
PMCPMC5886008

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.