ArticleSleep2018
Auditory stimulation of sleep slow oscillations modulates subsequent memory encoding through altered hippocampal function.
Article in Sleep, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 41 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
41 citing papers in PubMed, 1 synthesis or guideline pooled it.
- A Systematic Review of Closed-Loop Feedback Techniques in Sleep Studies-Related Issues and Future Directions.Sensors (Basel, Switzerland) · 2020Pooled it
- Acoustic stimulation as a promising technique to enhance slow-wave sleep in Alzheimer's disease: results of a pilot study.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2023Trial
- Trial
- Sleep loss disrupts the neural signature of successful learning.Cerebral cortex (New York, N.Y. : 1991) · 2023Trial
- Sleep slow oscillation emergence on the scalp as a renewal point process.PLoS computational biology · 2026Article
- Tone-Evoked Sleep Electroencephalographic Slow Oscillations as a Function of Peripheral Rhythms: New Insights Into the Brain-Heart Integration.Journal of sleep research · 2026Article
- The Effect of Closed-Loop Auditory Stimulation on Memory Consolidation and Sleep Physiology in an Ecological Setting.Journal of sleep research · 2026Article
- Article
- Memory consolidation during sleep: a facilitator of new learning?Neuropsychologia · 2026Review
- Modulating sleep: slow oscillation and spindle stimulation effects on physiology and memory.NPJ science of learning · 2026Article
- Protocol for modulating anesthesia delta oscillations using closed loop auditory stimulation.Frontiers in human neuroscience · 2026Article
- Closed-loop acoustic stimulation modified by cathodal tDCS is beneficial for retention.bioRxiv : the preprint server for biology · 2025Article
- Does overnight memory consolidation support next-day learning?Cognition · 2025Article
- Stimulating the Stimulated Cortex-Frontocortical Anodal Electric Stimulation Combined With Closed-Loop Acoustic Stimulation During Sleep Impairs Memory in Subjects With High Cognitive Ability.The European journal of neuroscience · 2025Article
- Unraveling the neurophysiological correlates of phase-specific enhancement of motor memory consolidation via slow-wave closed-loop targeted memory reactivation.Nature communications · 2025Article
- Does fragmented sleep mediate the relationship between deficits in sleep spindles and memory consolidation in schizophrenia?Sleep advances : a journal of the Sleep Research Society · 2025Article
- Optimizing automated phase-targeted auditory stimulation protocols for procedural memory consolidation during sleep in a home setting.Sleep advances : a journal of the Sleep Research Society · 2025Article
- Closed-Loop Auditory Stimulation (CLAS) During Sleep Augments Language and Discovery Learning.Brain sciences · 2024Article
- Can Neuromodulation Improve Sleep and Psychiatric Symptoms?Current psychiatry reports · 2024Review
- Acoustically evoked K-complexes together with sleep spindles boost verbal declarative memory consolidation in healthy adults.Scientific reports · 2024Article
Corrections and comments
- Erratum issued
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Study Objectives: Slow oscillations (SO) during sleep contribute to the consolidation of learned material. How the encoding of declarative memories during subsequent wakefulness might benefit from their enhancement during sleep is less clear. In this study, we investigated the impact of acoustically enhanced SO during a nap on subsequent encoding of declarative material. Methods: Thirty-seven healthy young adults were studied under two conditions: stimulation (STIM) and no stimulation (SHAM), in counter-balanced order following a night of sleep restriction (4 hr time-in-bed [TIB]). In the STIM condition, auditory tones were phase-locked to the SO up-state during a 90 min nap opportunity. In the SHAM condition, corresponding time points were marked but tones were not presented. Thirty minutes after awakening, participants encoded pictures while undergoing fMRI. Picture recognition was tested 60 min later. Results: Acoustic stimulation augmented SO across the group, but there was no group level benefit on memory. However, the magnitude of SO enhancement correlated with greater recollection. SO enhancement was also positively correlated with hippocampal activation at encoding. Although spindle activity increased, this did not correlate with memory benefit or shift in hippocampal signal. Conclusions: Acoustic stimulation during a nap can benefit encoding of declarative memories. Hippocampal activation positively correlated with SO augmentation.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.