Evidence map›Paper›PMID 29425208›Full record

ArticlePloS one2018

Estimation of linkage disequilibrium and analysis of genetic diversity in Korean chicken lines.

Dongwon Seo, Doo Ho Lee, Nuri Choi, Pita Sudrajad, Seung-Hwan Lee, Jun-Heon Lee

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
3.1field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 23 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Dongwon SeoDivision of Animal and Dairy Science, Chungnam National University, Daejeon, Korea.
Doo Ho LeeDivision of Animal and Dairy Science, Chungnam National University, Daejeon, Korea.
Nuri ChoiDivision of Animal and Dairy Science, Chungnam National University, Daejeon, Korea.
Pita SudrajadIndonesian Agency for Agricultural Research and Development, Ministry of Agriculture, South Jakarta, Indonesia.
Seung-Hwan LeeDivision of Animal and Dairy Science, Chungnam National University, Daejeon, Korea.
Jun-Heon LeeDivision of Animal and Dairy Science, Chungnam National University, Daejeon, Korea.ORCID 0000-0003-3996-9209
Chungnam National University · KRMinistry of Agriculture · ID

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The development of genetic markers for animal breeding is an effective strategy to reduce the time and cost required to improve economically important traits. To implement genomic selection in the multibreed chicken population of Korea, an understanding of the linkage disequilibrium (LD) status of the target population is essential. In this study, we performed population genetic analyses to investigate LD decay, the effective population size, and breed diversity using 600K high-density single nucleotide polymorphism genotypes of 189 native chickens in 14 lines (including Korean native chicken, imported and adapted purebred and commercial chickens). The results indicated that commercial native chickens have less calculated LD (average, r2 = 0.13-0.26) and purebred native chickens have more calculated LD (average, r2 = 0.24-0.37) across the entire genome. The effective population sizes of the examined lines showed patterns opposite to those of population LD. The phylogeny and admixture analyses showed that commercial and purebred chickens were well distinguished, except for Rhode Island Red (RIR) purebred lines of NC (NIAS_RIR_C) and ND (NIAS_RIR_D). These lines are difficult to distinguish clearly because they originated from the same respective breeds. The results of this study may provide important information for the development of genetic markers that can be used in breeding to improve the economic traits of native chickens.

Indexed as

Genetic VariationLinkage DisequilibriumAnimalsChickensPolymorphism, Single NucleotideRepublic of Korea

Identifiers

PMID29425208
PMCPMC5806858
OpenAlexW2790108980

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.