Evidence map›Paper›PMID 29424711›Full record

ArticlePhysics in medicine and biology2018

Using the cavitation collapse time to indicate the extent of histotripsy-induced tissue fractionation.

J J Macoskey, S W Choi, T L Hall, E Vlaisavljevich, J E Lundt, F T Lee, E Johnsen, C A Cain, Z Xu

Abstract read
In one paragraph

Article in Physics in medicine and biology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
1.2field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 32 citations in OpenAlex.

  1. Article
  2. Chirp-Coded Subharmonic Imaging With Volterra Filtering: Histotripsy Bubble Cloud Assessment In Vitro and Ex Vivo.IEEE transactions on ultrasonics, ferroelectrics, and frequency control · 2025
    Article
  3. Article
  4. Article
  5. In Vivo Cavitation-Based Aberration Correction of Histotripsy in Porcine Liver.IEEE transactions on ultrasonics, ferroelectrics, and frequency control · 2024
    Article
  6. Histotripsy: A Method for Mechanical Tissue Ablation with Ultrasound.Annual review of biomedical engineering · 2024
    Review
  7. Article
  8. Insights fromInternational journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group · 2024
    Review
  9. Article
  10. Article
  11. A review of the development of histotripsy for extremity tumor ablation with a canine comparative oncology model to inform human treatments.International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group · 2023
    Review
  12. Article
  13. Article
  14. Histotripsy for the Treatment of Cholangiocarcinoma Liver Tumors: In Vivo Feasibility and Ex Vivo Dosimetry Study.IEEE transactions on ultrasonics, ferroelectrics, and frequency control · 2021
    Article
  15. Article
  16. Cavitation in soft matter.Proceedings of the National Academy of Sciences of the United States of America · 2020
    Article
  17. Article
  18. Review
  19. Article
  20. Soft-Tissue Aberration Correction for Histotripsy.IEEE transactions on ultrasonics, ferroelectrics, and frequency control · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

J J MacoskeyDepartment of Biomedical Engineering, University of Michigan, Ann Arbor, MI, United States of America.ORCID 0000-0002-2776-230X
S W ChoiDepartment of Biomedical Engineering, University of Michigan, Ann Arbor, MI, United States of America.
T L HallDepartment of Biomedical Engineering, University of Michigan, Ann Arbor, MI, United States of America.
E VlaisavljevichDepartment of Biomedical Engineering and Mechanics, Virginia Tech, Blacksburg, VA, United States of America.
J E LundtDepartment of Biomedical Engineering, University of Michigan, Ann Arbor, MI, United States of America.
F T LeeDepartment of Radiology, University of Wisconsin, Madison, WI, United States of America.
E JohnsenDepartment of Mechanical Engineering, University of Michigan, Ann Arbor, MI, United States of America.
C A CainDepartment of Biomedical Engineering, University of Michigan, Ann Arbor, MI, United States of America.
Z XuDepartment of Biomedical Engineering, University of Michigan, Ann Arbor, MI, United States of America.
University of Michigan · USUniversity of Wisconsin–Madison · USVirginia Tech · US

Funding

Image-Guided Non-Invasive Ultrasonic Thrombolysis Using HistotripsyR01EB008998 · NIBIB · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI XU, ZHEN · 2008 to 2017
$4.5M
Novel, Noninvasive, Rapid Tumor Ablation Technology using HistotripsyR01CA211217 · NCI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI XU, ZHEN · 2018 to 2022
$2.7M
Novel Ultrasonic Technology to Treat Hemorrhagic StrokeR21NS093121 · NINDS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI XU, ZHEN · 2015 to 2016
$426k
NCI NIH HHS R01 CA211217NIBIB NIH HHS R01 EB008998NINDS NIH HHS R21 NS093121
6 · The paper itself

Abstract

Histotripsy is an ultrasonic tissue ablation method based on acoustic cavitation. It has been shown that cavitation dynamics change depending on the mechanical properties of the host medium. During histotripsy treatment, the target-tissue is gradually fractionated and eventually liquefied to acellular homogenate. In this study, the change in the collapse time (t

Indexed as

Phantoms, ImagingAblation TechniquesAlgorithmsAnimalsCattleDose Fractionation, RadiationHigh-Intensity Focused Ultrasound AblationLithotripsyLiverRadiation Dosage

Identifiers

PMID29424711
PMCPMC6042290
OpenAlexW2790369208

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.