Evidence map›Paper›PMID 29424685›Full record

ArticleeLife2018

Global morphogenetic flow is accurately predicted by the spatial distribution of myosin motors.

Sebastian J Streichan, Matthew F Lefebvre, Nicholas Noll, Eric F Wieschaus, Boris I Shraiman

Abstract read
In one paragraph

Article in eLife, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 87 papers.

0numbers the graph read from it
0cells of the map it votes in
87citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

87 citing papers in PubMed.

  1. Article
  2. bioRxiv : the preprint server for biology · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Sociohydrodynamics: Data-driven modeling of social behavior.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  7. Dynamical systems of fate and form in development.Seminars in cell & developmental biology · 2025
    Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Stochastic morphological swings inProceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. A geometric-tension-dynamics model of epithelial convergent extension.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article

27 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Sebastian J StreichanKavli Institute of Theoretical Physics, University of California, Santa Barbara, United States.
Matthew F LefebvreDepartment of Molecular Biology, Princeton University, Princeton, United States.
Nicholas NollDepartment of Physics, University of California, Santa Barbara, United States.ORCID http://orcid.org/0000-0003-1698-7500
Eric F WieschausDepartment of Molecular Biology, Princeton University, Princeton, United States.ORCID https://orcid.org/0000-0002-0727-3349
Boris I ShraimanKavli Institute of Theoretical Physics, University of California, Santa Barbara, United States.ORCID http://orcid.org/0000-0003-0886-8990

Funding

Tissue flow genetics: using cartography to reveal forces driving morphogenesisR00HD088708 · NICHD · UNIVERSITY OF CALIFORNIA SANTA BARBARA · PI STREICHAN, SEBASTIAN J · 2018 to 2020
$659k
Tissue flow genetics: using cartography to reveal forces driving morphogenesisK99HD088708 · NICHD · UNIVERSITY OF CALIFORNIA SANTA BARBARA · PI STREICHAN, SEBASTIAN J · 2016 to 2017
$287k
Howard Hughes Medical InstituteNICHD NIH HHS K99 HD088708NICHD NIH HHS NICHD 1K99HD088708NICHD NIH HHS R00 HD088708
6 · The paper itself

Abstract

During embryogenesis tissue layers undergo morphogenetic flow rearranging and folding into specific shapes. While developmental biology has identified key genes and local cellular processes, global coordination of tissue remodeling at the organ scale remains unclear. Here, we combine

Indexed as

GastrulationAnimalsDrosophilaMicroscopyMyosinsSpatio-Temporal AnalysisMyosinsbiophysicscomputational biologyD. melanogastermorphogenesissystems biologytissue mechanics

Identifiers

PMID29424685
PMCPMC5843464

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.