ArticleAging & mental health2019
Optimal metrics for identifying long term patterns of depression in older HIV-infected and HIV-uninfected men who have sex with men.
Article in Aging & mental health, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed, 18 citations in OpenAlex.
- Article
- The Intersectional Influence of Experienced Stigma on Clinically Significant Depressive Symptoms Among Gay, Bisexual, and Other Men Who Have Sex with Men.Journal of homosexuality · 2026Article
- HIV, Nephrotoxic Medications, and Chronic Kidney Disease: Prevalence, Risk Factors, and Mediation Analyses Among People With and Without HIV Enrolled in the Multicenter AIDS Cohort Study (MACS) / Women's Interagency HIV Study (WIHS) Combined Cohort Study.medRxiv : the preprint server for health sciences · 2025Article
- Assessing psychological resilience and its influencing factors in the MSM population by machine learning.Scientific reports · 2025Article
- The Relationship Between Posttraumatic Stress Disorder and Alcohol Misuse and Smoking Among Aging Men Who Have Sex With Men: No Evidence of Exercise or Volunteering Impact.Journal of aging and health · 2024Article
- Family Functioning and Depressive Symptoms Among HIV-Positive Men Who Have Sex with Men: Mediating Roles of Stigma and Resilience.Psychology research and behavior management · 2024Article
- HIV-related stigma, depression and suicidal ideation among HIV-positive MSM in China: a moderated mediation model.BMC public health · 2023Article
- Biopsychosocial Health Outcomes and Experienced Intersectional Stigma in a Mixed HIV Serostatus Longitudinal Cohort of Aging Sexual Minority Men, United States, 2008‒2019.American journal of public health · 2022Article
- Article
- Social inequalities contribute to racial/ethnic disparities in depressive symptomology among men who have sex with men.Social psychiatry and psychiatric epidemiology · 2021Article
- Does Social Support Predict Depressive Symptoms? A Longitudinal Study of Midlife and Older Men Who Have Sex with Men from the Multicenter AIDS Cohort Study.Annals of LGBTQ public and population health · 2021Article
- The relationship between diabetes and depressive symptoms in men with or at risk of HIV infection.HIV medicine · 2021Article
- Victimization in Early Adolescence, Stress, and Depressive Symptoms Among Aging Sexual Minority Men: Findings from the Multicenter AIDS Cohort Study.LGBT health · 2020Article
- Inflammation and Risk of Depression in HIV: Prospective Findings From the Multicenter AIDS Cohort Study.American journal of epidemiology · 2019Article
- Increased risk of depression in non-depressed HIV infected men with sleep disturbance: Prospective findings from the Multicenter AIDS Cohort Study.EBioMedicine · 2018Article
- Family Relationships, Resilience, and Quality of Life in People Living with HIV and Their Family Members: An Actor-Partner Interdependence Mediation Model.Journal of the International Association of Providers of AIDS CareArticle
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Authors and funding
9 authors at 2 institutions in 1 country.
Funding
Abstract
objectivesCenter of Epidemiologic Studies-Depression Scale (CES-D) provides a snapshot of symptom severity at a single point in time. However, the best way of using CES-D to classify long-term depression is unclear.
methodTo identify long-term depression among HIV-infected and HIV-uninfected 50+ year-old men who have sex with men (MSM) with at least 5 years of follow-up, we compared sensitivities and specificities of CES-D-based metrics (baseline CES-D; four consecutive CES-Ds; group-based trajectory models) thresholded at 16 and 20 to a clinician's evaluation of depression phenotype based on all available data including CES-D history, depression treatment history, drug use history, HIV disease factors, and demographic characteristics.
resultsA positive depressive phenotype prevalence was common among HIV-infected (prevalence = 33.1%) and HIV-uninfected MSM (prevalence = 23.2%). Compared to the depressive phenotype, trajectory models of CES-D≥20 provided highest specificities among HIV-infected (specificity = 99.9%, 95% Confidence Interval [CI]:99.4%-100.0%) and HIV-uninfected MSM (specificity = 99.0%, 95% CI:97.4%-99.7%). Highest sensitivities resulted from classifying baseline CES-D ≥ 16 among HIV-infected MSM (sensitivity = 75.0%, 95% CI:67.3%-81.7%) and four consecutive CES-Ds ≥ 16 among HIV-uninfected MSM (sensitivity = 81.0%, 95% CI:73.7%-87.0%).
conclusionChoice of method should vary, depending on importance of false positive or negative rate for long-term depression in HIV-infected and HIV-uninfected MSM.
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