Evidence map›Paper›PMID 29424420›Full record

ArticleThe Journal of comparative neurology2018

Neuroanatomical details of the lateral neurons of Drosophila melanogaster support their functional role in the circadian system.

Frank K Schubert, Nicolas Hagedorn, Taishi Yoshii, Charlotte Helfrich-Förster, Dirk Rieger

Open access · bronzeAbstract read
In one paragraph

Article in The Journal of comparative neurology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers.

0numbers the graph read from it
0cells of the map it votes in
48citing papers in PubMed
4.2field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

48 citing papers in PubMed, 92 citations in OpenAlex.

  1. Article
  2. A functional clock in only two dorsal clock neurons is sufficient to restore the basal circadian activity pattern ofProceedings of the National Academy of Sciences of the United States of America · 2025
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  20. Life science alliance · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Frank K SchubertNeurobiology and Genetics, Theodor-Boveri Institute, Biocenter, University of Würzburg, Würzburg, 97074, Germany.
Nicolas HagedornNeurobiology and Genetics, Theodor-Boveri Institute, Biocenter, University of Würzburg, Würzburg, 97074, Germany.
Taishi YoshiiGraduate School of Natural Science and Technology, Okayama University, Okayama, 700-8530, Japan.
Charlotte Helfrich-FörsterNeurobiology and Genetics, Theodor-Boveri Institute, Biocenter, University of Würzburg, Würzburg, 97074, Germany.
Dirk RiegerNeurobiology and Genetics, Theodor-Boveri Institute, Biocenter, University of Würzburg, Würzburg, 97074, Germany.ORCID 0000-0001-5597-5858
University of Würzburg · DEOkayama University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Drosophila melanogaster is a long-standing model organism in the circadian clock research. A major advantage is the relative small number of about 150 neurons, which built the circadian clock in Drosophila. In our recent work, we focused on the neuroanatomical properties of the lateral neurons of the clock network. By applying the multicolor-labeling technique Flybow we were able to identify the anatomical similarity of the previously described E2 subunit of the evening oscillator of the clock, which is built by the 5th small ventrolateral neuron (5th s-LN

Indexed as

AnimalsAnimals, Genetically ModifiedBrainCircadian ClocksCLOCK ProteinsDrosophila melanogasterDrosophila ProteinsMicroscopy, ConfocalNeuroanatomyNeuronsTranscription FactorsClk protein, DrosophilaCLOCK ProteinsDrosophila ProteinsGAL4 protein, DrosophilaTranscription Factorscircadian clock neuronsDrosophila melanogasterflybowmorphologyRRID: AB_141780RRID: AB_2314041RRID: AB_2314242RRID: AB_2315311RRID: AB_2315460RRID: AB_2534096RRID: AB_2534121RRID: AB_2535804RRID: AB_2535812RRID: AB_2536186RRID: AB_2536611RRID: AB_300798RRID: AB_760350

Identifiers

PMID29424420
PMCPMC5873451
OpenAlexW2792035889

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.