Evidence map›Paper›PMID 29423817›Full record

ArticleMolecular neurobiology2018

Characterization of Behavioral, Signaling and Cytokine Alterations in a Rat Neurodevelopmental Model for Schizophrenia, and Their Reversal by the 5-HT

Sinead E Shortall, Ola H Negm, Maxine Fowler, Lucy C Fairclough, Patrick J Tighe, Peter M Wigmore, Madeleine V King

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecular neurobiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.8field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 15 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Impact of 5-HTCells · 2023
    Review
  5. The Phenoxyalkyltriazine Antagonists for 5-HTInternational journal of molecular sciences · 2021
    Article
  6. Review
  7. Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Sinead E ShortallSchool of Life Sciences, Medical School, Queen's Medical Centre, The University of Nottingham, Nottingham, NG7 2UH, UK.
Ola H NegmSchool of Medicine, Medical School, Queen's Medical Centre, The University of Nottingham, Nottingham, NG7 2UH, UK.
Maxine FowlerSchool of Life Sciences, Medical School, Queen's Medical Centre, The University of Nottingham, Nottingham, NG7 2UH, UK.
Lucy C FaircloughSchool of Life Sciences, Medical School, Queen's Medical Centre, The University of Nottingham, Nottingham, NG7 2UH, UK.
Patrick J TigheSchool of Life Sciences, Medical School, Queen's Medical Centre, The University of Nottingham, Nottingham, NG7 2UH, UK.
Peter M WigmoreSchool of Life Sciences, Medical School, Queen's Medical Centre, The University of Nottingham, Nottingham, NG7 2UH, UK.
Madeleine V KingSchool of Life Sciences, Medical School, Queen's Medical Centre, The University of Nottingham, Nottingham, NG7 2UH, UK. madeleine.king@nottingham.ac.uk.
University of Nottingham · GBQueen's Medical Centre · GB

Funding

University of Nottingham Not applicable
6 · The paper itself

Abstract

Post-weaning social isolation of rats produces neuroanatomical, neurochemical and behavioral alterations resembling some core features of schizophrenia. This study examined the ability of the 5-HT

Indexed as

Behavior, AnimalSignal TransductionAnimalsCell ProliferationConditioning, PsychologicalCytokinesDiscrimination, PsychologicalDisease Models, AnimalFreezing Reaction, CatalepticHippocampusKi-67 AntigenMotor ActivityPiperazinesPrepulse InhibitionRatsReceptors, SerotoninCytokinesKi-67 AntigenPiperazinesReceptors, SerotoninSB 399885serotonin 6 receptorSulfonamides5-HT6 receptorCytokinesHippocampusJNK mitogen-activated protein kinasesSchizophreniaSocial isolation

Identifiers

PMID29423817
PMCPMC6096968
OpenAlexW2786547465

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.