Evidence map›Paper›PMID 29423697›Full record

ArticleEnvironmental science and pollution research international2018

Probing the toxic mechanism of bisphenol A with acid phosphatase at the molecular level.

Mengchen Xu, Rui Zhang, Wei Song, Wansong Zong, Rutao Liu

Abstract read
PubMed Publisher
In one paragraph

Article in Environmental science and pollution research international, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.8field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 10 citations in OpenAlex.

  1. A biophysical probe on the binding of 2-mercaptothioazoline to bovine hemoglobin.Environmental science and pollution research international · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Mengchen XuSchool of Environmental Science and Engineering, China -America CRC for Environment & Health, Shandong Province, Shandong University, 27# Shanda South Road, Jinan, 250100, People's Republic of China.
Rui ZhangSchool of Environmental Science and Engineering, China -America CRC for Environment & Health, Shandong Province, Shandong University, 27# Shanda South Road, Jinan, 250100, People's Republic of China.
Wei SongSchool of Environmental Science and Engineering, China -America CRC for Environment & Health, Shandong Province, Shandong University, 27# Shanda South Road, Jinan, 250100, People's Republic of China.
Wansong ZongCollege of Population, Resources and Environment, Shandong Normal University, 88# East Wenhua Road, Jinan, 250014, People's Republic of China.
Rutao LiuSchool of Environmental Science and Engineering, China -America CRC for Environment & Health, Shandong Province, Shandong University, 27# Shanda South Road, Jinan, 250100, People's Republic of China. rutaoliu@sdu.edu.cn.
Shandong University · CNShandong Normal University · CN

Funding

NSFC 21277081, 21477067 and 21507071Science and Technology Development Plan of Shandong Province 2014GSF117027
6 · The paper itself

Abstract

As an endocrine-disrupting chemical, bisphenol A (BPA), can affect normal endocrine function of hormone. This paper studied the toxic effect of BPA on acid phosphatase at the molecular level by multi-spectroscopic measurements, molecular docking, and enzyme activity experiment. BPA could enhance the fluorescence intensity, change the structure, and cause an increased hydrophobicity of acid phosphatase. Hydrogen bond interaction and van der Waals forces were the main forces to generate the BPA-acid phosphatase complex on account of the negative ΔH (- 36.92 kJ mol

Indexed as

Acid PhosphataseBenzhydryl CompoundsBinding SitesBisphenol A CompoundsEndocrine DisruptorsHydrogen BondingMolecular Docking SimulationPhenolsProtein BindingProtein ConformationSpectrometry, FluorescenceSpectrophotometry, UltravioletAcid PhosphataseBenzhydryl Compoundsbisphenol ABisphenol A CompoundsEndocrine DisruptorsPhenolsAcid phosphataseBisphenol AEnzyme activity assayInteraction mechanismsMolecular dockingMulti-spectroscopic measurements

Identifiers

PMID29423697
OpenAlexW2789826813

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.