Evidence map›Paper›PMID 29423615›Full record

ArticleJournal of neurology2018

Defining spasticity: a new approach considering current movement disorders terminology and botulinum toxin therapy.

Dirk Dressler, Roongroj Bhidayasiri, Saeed Bohlega, Pedro Chana, Hsin Fen Chien, Tae Mo Chung, Carlo Colosimo, Markus Ebke, Klemens Fedoroff, Bernd Frank and 15 more

Abstract read
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In one paragraph

Article in Journal of neurology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
44citing papers in PubMed, 4 pooled it
5.6field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

44 citing papers in PubMed, 4 syntheses or guidelines pooled it, 98 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Movement Disorders in MOGAD: A Systematic Review.Medicina (Kaunas, Lithuania) · 2026
    Pooled it
  4. Pooled it
  5. Article
  6. Observational
  7. Article
  8. The use of botulinum toxin for spasticity in people with spinal cord injury: a scoping review.European journal of physical and rehabilitation medicine · 2026
    Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Living With Spasticity During the COVID-19 Pandemic: A Qualitative Study of Patient, Carer and Physician Experiences.Health expectations : an international journal of public participation in health care and health policy · 2024
    Article
  15. Article
  16. Observational
  17. Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

25 authors at 20 institutions in 16 countries.

Dirk DresslerHead of Movement Disorders Section, Department of Neurology, Hannover Medical School, Carl-Neuberg-Str. 1, 30625, Hannover, Germany. dressler.dirk@mh-hannover.de.
Roongroj BhidayasiriChulalongkorn Centre for Excellence on Parkinson's Disease and Related Disorders, King Chulalongkorn Memorial Hospital, Bangkok, Thailand.
Saeed BohlegaDepartment of Neurology, King Faisal Specialist Hospital, Riyyad, Kingdom of Saudi Arabia.
Pedro ChanaDepartment of Neurology, University of Santiago de Chile, Santiago de Chile, Chile.
Hsin Fen ChienDepartment of Neurology, University of Sao Paulo, Sao Paulo, Brazil.
Tae Mo ChungUniversity of Sao Paulo, Sao Paulo, Brazil.
Carlo ColosimoAzienda Ospedaliera Santa Maria di Terni, Terni, Italy.
Markus EbkeMedian-Klinik Bad Salzuflen, Bad Salzuflen, Germany.
Klemens FedoroffGailtal-Klinik, Hermagor, Austria.
Bernd FrankHelios-Klinik Leezen, Leezen, Germany.
Ryuji KajiDepartment of Neurology, University of Tokushima, Tokushima, Japan.
Petr KanovskyDepartment of Neurology, Palacky University, Olomouc, Czech Republic.
Serdar KoçerCentre de Rééducation et Medicine Physique, Hôpital du Jura, Porrentruy, Switzerland.
Federico MicheliDepartment of Neurology, Hospital de Clínicas José de San Martín, University of Buenos Aires, Buenos Aires, Argentina.
Olga OrlovaClinic 'Cecil Plus', Moscow, Russia.
Sebastian PausDepartment of Neurology, Rheinische Friedrich-Wilhelms-Universität, Bonn, Germany.
Zvezdan PirtosekDepartment of Neurology, Ljubljana University Medical Centre, Ljubljana, Slovenia.
Maja ReljaDepartment of Neurology, University of Zagreb, Zagreb, Croatia.
Raymond L RosalesDepartment of Neurology, University of Santo Tomas Hospital, Manila, Philippines.
José Alberto Sagástegui-RodríguezDepartment of Neurology, University of Monterrey, Monterrey, Nueva Leon, Mexico.
Paul W SchoenleMaternus-Klinik für Rehabilitation, Bad Oeynhausen, Germany.
Gholam Ali ShahidiMovement Disorders Clinic, Department of Neurology, Rasoul-e Akram Hospital, Iran University of Medical Sciences, Tehran, Iran.
Sofia TimerbaevaFederal State Hospital for Treatment and Rehabilitation of the Ministry of Health and Social Development of the Russian Federation, Moscow, Russia.
Uwe WalterDepartment of Neurology, Rostock University, Rostock, Germany.
Fereshte Adib SaberiIAB-Interdisciplinary Working Group for Movement Disorders, Hamburg, Germany.
Universidade de São Paulo · BRAzienda Ospedaliera S.Maria · ITHelios Kliniken · DEHôpital du Jura Bernois · CHHospital de Clínicas "José de San Martín" · ARIran University of Medical Sciences · IRKing Chulalongkorn Memorial Hospital · THKing Faisal Specialist Hospital & Research Centre · SAKlinik Bad Oexen · DELaboratory Krone · DELjubljana University Medical Centre · SIMedizinische Hochschule Hannover · DEMinistry of Health of the Russian Federation · RUPalacký University Olomouc · CZTokushima University · JPUniversidad de Santiago de Chile · CLUniversity of Bonn · DEUniversity of Monterrey · MXUniversity of Rostock · DEUniversity of Santo Tomas Hospital · PH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Spasticity is a symptom occurring in many neurological conditions including stroke, multiple sclerosis, hypoxic brain damage, traumatic brain injury, tumours and heredodegenerative diseases. It affects large numbers of patients and may cause major disability. So far, spasticity has merely been described as part of the upper motor neurone syndrome or defined in a narrowed neurophysiological sense. This consensus organised by IAB-Interdisciplinary Working Group Movement Disorders wants to provide a brief and practical new definition of spasticity-for the first time-based on its various forms of muscle hyperactivity as described in the current movement disorders terminology. We propose the following new definition system: Spasticity describes involuntary muscle hyperactivity in the presence of central paresis. The involuntary muscle hyperactivity can consist of various forms of muscle hyperactivity: spasticity sensu strictu describes involuntary muscle hyperactivity triggered by rapid passive joint movements, rigidity involuntary muscle hyperactivity triggered by slow passive joint movements, dystonia spontaneous involuntary muscle hyperactivity and spasms complex involuntary movements usually triggered by sensory or acoustic stimuli. Spasticity can be described by a documentation system grouped along clinical picture (axis 1), aetiology (axis 2), localisation (axis 3) and additional central nervous system deficits (axis 4). Our new definition allows distinction of spasticity components accessible to BT therapy and those inaccessible. The documentation sheet presented provides essential information for planning of BT therapy.

Indexed as

Botulinum ToxinsHumansMovement DisordersMuscle SpasticityNeurotoxinsBotulinum ToxinsNeurotoxinsBotulinum toxin therapyContracturesDystoniaRigiditySpasmsSpasticityTreatment

Identifiers

PMID29423615
OpenAlexW2790788390

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.