ArticleArchives of virology2018
Detection and genetic characterization of bovine kobuvirus from calves in Egypt.
Article in Archives of virology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 25 citations in OpenAlex.
- Detection and Genetic Diversity of Bovine Kobuvirus in Diarrheic Calves in Türkiye: Genomic Characterization and Comparative B-Cell Epitope Analysis.Animals : an open access journal from MDPI · 2026Article
- Genomic sequencing and evolutionary analysis of bovine kobuvirus in Yunnan Province, China.BMC veterinary research · 2025Article
- Genomic characterization of novel bat kobuviruses in Madagascar: Implications for viral evolution and zoonotic risk.PloS one · 2025Article
- Identification of Recombinant Aichivirus D in Cattle, Italy.Animals : an open access journal from MDPI · 2024Article
- Molecular Detection and Genetic Characterization of Bovine Kobuvirus (BKV) in Diarrhoeic Calves in a Central Italy Herd.Transboundary and emerging diseases · 2023Article
- Detection and genome characterization of bovine kobuvirus (BKV) in faecal samples from diarrhoeic calves in Quebec, Canada.Transboundary and emerging diseases · 2022Article
- Literature Review: Coinfection in Young Ruminant Livestock-Pathogens (Basel, Switzerland) · 2022Review
- Development of a new TaqMan-based real-time RT-PCR assay for the specific detection of bovine kobuvirus.Frontiers in veterinary science · 2022Article
- Genomic features of first bovine astrovirus detected in Egypt.Virusdisease · 2021Article
- Detection and molecular characterization of kobuvirus from diarrheic goats in Minnesota.Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc · 2020Article
- Bovine Kobuvirus in Calves with Diarrhea, United States.Emerging infectious diseases · 2020Article
- First detection and genetic characterization of canine Kobuvirus in domestic dogs in Thailand.BMC veterinary research · 2019Article
Corrections and comments
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Authors and funding
7 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Kobuviruses are small non-enveloped RNA viruses that probably cause diarrhea in cattle and swine. Since its discovery in 2003, few studies have addressed bovine kobuvirus (BKoV; a species of Aichivirus B) infections. BKoV has been reported in Europe, Asia, and South America, suggesting a worldwide distribution. To investigate the presence of BKoV in Egypt, 36 fecal specimens from diarrheic calves in two different Egyptian provinces (Cairo and Sharkia) were screened by RT-PCR and 24 (66.7%) were found positive for BKoV. RNA from one of the positive samples (BKoV/Egy-1/KY407744) was subjected to next-generation sequencing to determine the complete BKoV genome sequence. When compared to the only recorded BKoV genome sequence (BKoV/U-1/AB084788), the studied strain showed 94 amino acid (aa) substitutions through its entire polyprotein (2463 aa), one nucleotide (nt) insertion and one nt deletion in the 2B gene and 4-nt deletions in the UTRs (2 each). Additionally, five VP1 and seven 3D sequences were obtained from other samples by using RT-PCR and Sanger sequencing. A discrepancy in the phylogenetic topography of VP1 and 3D was observed, where the Egyptian VP1 sequences were classified as a distinct cluster within the proposed lineage 1 (genotype A), which also contained strains from the UK, Brazil, and Japan. While, the 3D sequences from Cairo were related to those of Chinese strains unlike Sharkia ones that were more closer to Korean strains. To the best of our knowledge, this is the first detection and genomic characterization of BKoV in Egypt or indeed Africa.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.