Evidence map›Paper›PMID 29423347›Full record

ArticlePeerJ2018

Deficient mismatch repair and

Xiangyan Zhang, Wenwen Ran, Jie Wu, Hong Li, Huamin Liu, Lili Wang, Yujing Xiao, Xiaonan Wang, Yujun Li, Xiaoming Xing

Open access · goldAbstract read
In one paragraph

Article in PeerJ, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 2 pooled it
1.2field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 2 syntheses or guidelines pooled it, 21 citations in OpenAlex.

  1. Pooled it
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  11. Next-generation sequencing reveals heterogeneous genetic alterations in key signaling pathways of mismatch repair deficient colorectal carcinomas.Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc · 2020
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  13. PeerJ · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Xiangyan Zhang *Department of Pathology, Affiliated Hospital of Qingdao University, Qingdao, China.
Wenwen Ran *Department of Pathology, Affiliated Hospital of Qingdao University, Qingdao, China.
Jie WuDepartment of Pathology, Affiliated Hospital of Qingdao University, Qingdao, China.
Hong LiDepartment of Pathology, Affiliated Hospital of Qingdao University, Qingdao, China.
Huamin LiuDepartment of Oncology, Affiliated Hospital of Qingdao University, Qingdao, China.
Lili WangDepartment of Pathology, Affiliated Hospital of Qingdao University, Qingdao, China.
Yujing XiaoDepartment of Pathology, Affiliated Hospital of Qingdao University, Qingdao, China.
Xiaonan WangDepartment of Pathology, Affiliated Hospital of Qingdao University, Qingdao, China.
Yujun LiDepartment of Pathology, Affiliated Hospital of Qingdao University, Qingdao, China.
Xiaoming XingDepartment of Pathology, Affiliated Hospital of Qingdao University, Qingdao, China.
Affiliated Hospital of Qingdao University · CNQingdao University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo investigate the frequency and prognostic role of deficient mismatch repair (dMMR) and

methodsClinical and pathological information from 813 patients were reviewed and recorded. Expression of mismatch repair proteins was tested by immunohistochemistry. Mutation analyses for

resultsThe overall percentage of dMMR was 15.18% (121/797). The proportion of dMMR was higher in patients <50 years old (

conclusionsThis study confirms that the status of molecular markers involving mismatch repair status and

Indexed as

Clinicopathological characteristicsColorectal carcinomaDeficient mismatch repair (dMMR )KRAS mutationNRAS mutationPrognosis

Identifiers

PMID29423347
PMCPMC5804321
OpenAlexW2787392211

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.