Evidence map›Paper›PMID 29423130›Full record

ArticleNano research2011

Targeted Blue Nanoparticles as Photoacoustic Contrast Agent for Brain Tumor Delineation.

Aniruddha Ray, Xueding Wang, Yong-Eun Koo Lee, Hoe Jin Hah, Gwangseong Kim, Thomas Chen, Daniel A Orringer, Oren Sagher, Xiaojun Liu, Raoul Kopelman

Abstract read
In one paragraph

Article in Nano research, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Review
  5. Article
  6. Review
  7. ACS nano · 2019
    Article
  8. Review
  9. Review
  10. Article
  11. Article
  12. Article
  13. Review
  14. Prostate cancer characterization by optical contrast enhanced photoacoustics.Proceedings of SPIE--the International Society for Optical Engineering · 2016
    Article
  15. Lifetime-resolved Photoacoustic (LPA) Spectroscopy for monitoring Oxygen change and Photodynamic Therapy (PDT).Proceedings of SPIE--the International Society for Optical Engineering · 2016
    Article
  16. Review
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Aniruddha RayBiophysics, University of Michigan, Ann Arbor, MI 48109, USA.
Xueding WangDepartment of Radiology, University of Michigan, Ann Arbor, MI 48109, USA.
Yong-Eun Koo LeeDepartment of Chemistry, University of Michigan, Ann Arbor, MI 48109, USA.
Hoe Jin HahDepartment of Chemistry, University of Michigan, Ann Arbor, MI 48109, USA.
Gwangseong KimDepartment of Chemistry, University of Michigan, Ann Arbor, MI 48109, USA.
Thomas ChenDepartment of Neurosurgery, University of Michigan, Ann Arbor, MI 48109, USA.
Daniel A OrringerDepartment of Neurosurgery, University of Michigan, Ann Arbor, MI 48109, USA.
Oren SagherDepartment of Neurosurgery, University of Michigan, Ann Arbor, MI 48109, USA.
Xiaojun LiuInstitute of Acoustics, Nanjing University, Nanjing 210093, China.
Raoul KopelmanBiophysics, University of Michigan, Ann Arbor, MI 48109, USA.

Funding

Photonic Nanosonophores for Functional and Structural ImagingR01CA186769 · NCI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI KOPELMAN, RAOUL, WANG, XUEDING · 2014 to 2018
$1.6M
Nanobiophotonics Enabled Tumor Surgery and Intraoperative PDTR33CA125297 · NCI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI KOPELMAN, RAOUL · 2008 to 2010
$1.5M
NCI NIH HHS R01 CA186769NCI NIH HHS R33 CA125297
6 · The paper itself

Abstract

Distinguishing a tumor from non-neoplastic tissue is a challenging task during cancer surgery. Several attempts have been made to use visible or fluorescent agents to aid in the visualization of a tumor during surgery. We describe a novel method to delineate brain tumors, using a highly sensitive photoacoustic imaging technique that is enhanced by tumor-targeting blue nanoparticles serving as a contrast agent. Experiments on phantoms and on rat brains,

Indexed as

Brain tumorCoomassie Blue dyeF3 peptidephotoacoustic imagingsurgerytargeted nanoparticles

Identifiers

PMID29423130
PMCPMC5800421

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.