Evidence map›Paper›PMID 29423073›Full record

ArticleOncotarget2018

Cognition, serum BDNF levels, and BDNF Val66Met polymorphism in type 2 diabetes patients and healthy controls.

Yan-Feng Zhen, Xing-Yu Liu, Dong-Hao Zhou, Xiangdong Du, Guangzhong Yin, Yingyang Zhang, Hui Fang, Gang Xu, Jair C Soares, Xiang Yang Zhang

Open access · diamondAbstract read
In one paragraph

Article in Oncotarget, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
0.8field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it, 28 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 2 countries.

Yan-Feng ZhenDepartment of Endocrinology, Tangshan Gongren Hospital, Tangshan, China.
Xing-Yu LiuDepartment of Neurosurgery, Tangshan Gongren Hospital, Tangshan, China.
Dong-Hao ZhouDepartment of Endocrinology, Linyi People's Hospital, Linyi, China.
Xiangdong DuSuzhou Psychiatric Hospital, The Affiliated Guangji Hospital of Soochow University, Suzhou, China.
Guangzhong YinSuzhou Psychiatric Hospital, The Affiliated Guangji Hospital of Soochow University, Suzhou, China.
Yingyang ZhangSuzhou Psychiatric Hospital, The Affiliated Guangji Hospital of Soochow University, Suzhou, China.
Hui FangDepartment of Endocrinology, Tangshan Gongren Hospital, Tangshan, China.
Gang XuDepartment of Burn, Tangshan Gongren Hospital, Tangshan, China.
Jair C SoaresDepartment of Psychiatry and Behavioral Sciences, The University of Texas Health Science Center at Houston, Houston, TX, USA.
Xiang Yang ZhangDepartment of Psychiatry and Behavioral Sciences, The University of Texas Health Science Center at Houston, Houston, TX, USA.
Tangshan Gongren Hospital · CNSuzhou Guangji Hospital · CNThe University of Texas Health Science Center at Houston · USLinyi People's Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

aimsType 2 diabetes (T2DM) is associated with cognitive deficits. However, their pathophysiological mechanisms are still unknown. Recent study suggests that brain-derived neurotrophic factor (BDNF) is correlated with cognitive deficits in T2DM patients. This study was to determine whether altered serum BDNF levels and cognitive deficits depended on the

resultsThe

conclusions

methodsWe recruited 311 T2DM patients and 346 healthy controls and compared them on the Repeatable Battery for the Assessment of Neuropsychological Status (RBANS), serum BDNF levels, and the

Indexed as

associationbrain-derived neurotrophic factorcognitionpolymorphismtype 2 diabetes

Identifiers

PMID29423073
PMCPMC5790490
OpenAlexW2772808567

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.