Evidence map›Paper›PMID 29423006›Full record

ArticleAmerican journal of translational research2018

Umbilical cord mesenchymal stem cell transplantation in the treatment of multiple sclerosis.

Mingyao Meng, Ying Liu, Wenju Wang, Chuanyu Wei, Feifei Liu, Zhiqin Du, Yanhua Xie, Weiwei Tang, Zongliu Hou, Qihan Li

Open access · greenAbstract read
In one paragraph

Article in American journal of translational research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 1 pooled it
3.3field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 1 synthesis or guideline pooled it, 44 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Review
  4. Review
  5. Review
  6. Review
  7. Review
  8. Review
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  10. Review
  11. Stem cell-based therapy for human diseases.Signal transduction and targeted therapy · 2022
    Review
  12. Review
  13. Article
  14. Review
  15. Article
  16. Stem Cell Therapies for Progressive Multiple Sclerosis.Frontiers in cell and developmental biology · 2021
    Review
  17. Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Mingyao MengInstitute of Medical Biology, Chinese Academy of Medical Sciences and Peking Union Medical CollegeKunming 650118, China.
Ying LiuYan'an Affiliated Hospital of Kunming Medical University, Yunnan Cell Biology and Clinical Translation Research Center, Key Laboratory of Tumor Immunological Prevention and Treatment of Yunnan ProvinceKunming 650051, Yunnan, People's Republic of China.
Wenju WangYan'an Affiliated Hospital of Kunming Medical University, Yunnan Cell Biology and Clinical Translation Research Center, Key Laboratory of Tumor Immunological Prevention and Treatment of Yunnan ProvinceKunming 650051, Yunnan, People's Republic of China.
Chuanyu WeiYan'an Affiliated Hospital of Kunming Medical University, Yunnan Cell Biology and Clinical Translation Research Center, Key Laboratory of Tumor Immunological Prevention and Treatment of Yunnan ProvinceKunming 650051, Yunnan, People's Republic of China.
Feifei LiuYan'an Affiliated Hospital of Kunming Medical University, Yunnan Cell Biology and Clinical Translation Research Center, Key Laboratory of Tumor Immunological Prevention and Treatment of Yunnan ProvinceKunming 650051, Yunnan, People's Republic of China.
Zhiqin DuYan'an Affiliated Hospital of Kunming Medical University, Yunnan Cell Biology and Clinical Translation Research Center, Key Laboratory of Tumor Immunological Prevention and Treatment of Yunnan ProvinceKunming 650051, Yunnan, People's Republic of China.
Yanhua XieYan'an Affiliated Hospital of Kunming Medical University, Yunnan Cell Biology and Clinical Translation Research Center, Key Laboratory of Tumor Immunological Prevention and Treatment of Yunnan ProvinceKunming 650051, Yunnan, People's Republic of China.
Weiwei TangYan'an Affiliated Hospital of Kunming Medical University, Yunnan Cell Biology and Clinical Translation Research Center, Key Laboratory of Tumor Immunological Prevention and Treatment of Yunnan ProvinceKunming 650051, Yunnan, People's Republic of China.
Zongliu HouYan'an Affiliated Hospital of Kunming Medical University, Yunnan Cell Biology and Clinical Translation Research Center, Key Laboratory of Tumor Immunological Prevention and Treatment of Yunnan ProvinceKunming 650051, Yunnan, People's Republic of China.
Qihan LiInstitute of Medical Biology, Chinese Academy of Medical Sciences and Peking Union Medical CollegeKunming 650118, China.
Kunming Medical University · CNChinese Academy of Medical Sciences & Peking Union Medical College · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To investigate the clinical efficacy and safety of umbilical cord mesenchymal stem cell (UCMSC) transplantation for treating multiple sclerosis (MS), the patients with MS were recruited and treated with UCMSC. The procedure of preparing UCMSC was in accordance with the standards formulated by the International Society for Cell Biology. Cell surface markers, multiple differentiation potential and safety of UCMSC for transplantation were detected. The number of cells in each infusion was 1 to 2×10

Indexed as

clinical efficacymultiple sclerosistransplantationUmbilical cord mesenchymal stem cell

Identifiers

PMID29423006
PMCPMC5801359
OpenAlexW2980321312

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.