Evidence map›Paper›PMID 29422894›Full record

ReviewFrontiers in immunology2018

The B-Cell Follicle in HIV Infection: Barrier to a Cure.

Matthew P Bronnimann, Pamela J Skinner, Elizabeth Connick

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in immunology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 60 papers.

0numbers the graph read from it
0cells of the map it votes in
60citing papers in PubMed
6.1field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

60 citing papers in PubMed, 85 citations in OpenAlex.

  1. Trial
  2. Protein-dependent CD4iScience · 2026
    Article
  3. Review
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Review
  10. Review
  11. Compartmental structure in the secondary lymphoid tissue can slow downJournal of the Royal Society, Interface · 2025
    Article
  12. Article
  13. Article
  14. Article
  15. Antigen Presenting Cell-Mediated HIV-1Medical research archives · 2023
    Article
  16. Cytolytic CD8Science immunology · 2023
    Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Matthew P BronnimannDivision of Infectious Disease, Department of Medicine, University of Arizona, Tucson, AZ, United States.
Pamela J SkinnerDepartment of Veterinary and Biomedical Sciences, University of Minnesota, St. Paul, MN, United States.
Elizabeth ConnickDivision of Infectious Disease, Department of Medicine, University of Arizona, Tucson, AZ, United States.
University of Arizona · USUniversity of Minnesota · US

Funding

BELIEVE: Bench to Bed Enhanced Lymphocyte Infusions to Engineer Viral EradicationUM1AI126617 · NIAID · WEILL MEDICAL COLL OF CORNELL UNIV · PI JONES, R. BRAD, NIXON, DOUGLAS F · 2016 to 2020
$28.1M
Mechanisms Underlying Persistent Lentivirus Replication in Follicular T CellsR01AI096966 · NIAID · UNIVERSITY OF COLORADO DENVER · PI CONNICK, ELIZABETH, SKINNER, PAMELA J · 2013 to 2017
$4.2M
NIAID NIH HHS R01 AI096966NIAID NIH HHS UM1 AI126617
6 · The paper itself

Abstract

The majority of HIV replication occurs in secondary lymphoid organs (SLOs) such as the spleen, lymph nodes, and gut-associated lymphoid tissue. Within SLOs, HIV RNA

Indexed as

B-LymphocytesDendritic Cells, FollicularGerminal CenterHIV-1HIV InfectionsHumansIntraepithelial LymphocytesKiller Cells, NaturalT-Lymphocytes, Helper-InducerT-Lymphocytes, RegulatoryVirus ReplicationB cell follicle sanctuarycytotoxic T-cell (CTL)follicular dendritic cellgamma delta T cellsHIV cure researchNK cellsregulatory T cellsT follicular helper cell subsets

Identifiers

PMID29422894
PMCPMC5788973
OpenAlexW2793402562

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.