Evidence map›Paper›PMID 29422893›Full record

ArticleFrontiers in immunology2017

Immunosuppressive Mesenchymal Stromal Cells Derived from Human-Induced Pluripotent Stem Cells Induce Human Regulatory T Cells

Clémence Roux, Gaëlle Saviane, Jonathan Pini, Nourhène Belaïd, Gihen Dhib, Christine Voha, Lidia Ibáñez, Antoine Boutin, Nathalie M Mazure, Abdelilah Wakkach and 2 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
4.7field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 46 citations in OpenAlex.

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  9. Translating MSC Therapy in the Age of Obesity.Frontiers in immunology · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 1 country.

Clémence RouxLP2M, CNRS-UMR 7370, Faculty of Medicine, Nice, France.
Gaëlle SavianeLP2M, CNRS-UMR 7370, Faculty of Medicine, Nice, France.
Jonathan PiniLP2M, CNRS-UMR 7370, Faculty of Medicine, Nice, France.
Nourhène BelaïdLP2M, CNRS-UMR 7370, Faculty of Medicine, Nice, France.
Gihen DhibLP2M, CNRS-UMR 7370, Faculty of Medicine, Nice, France.
Christine VohaLP2M, CNRS-UMR 7370, Faculty of Medicine, Nice, France.
Lidia IbáñezLP2M, CNRS-UMR 7370, Faculty of Medicine, Nice, France.
Antoine BoutinLP2M, CNRS-UMR 7370, Faculty of Medicine, Nice, France.
Nathalie M MazureUniversité Nice-Sophia Antipolis, Nice, France.
Abdelilah WakkachLP2M, CNRS-UMR 7370, Faculty of Medicine, Nice, France.
Claudine Blin-WakkachLP2M, CNRS-UMR 7370, Faculty of Medicine, Nice, France.
Matthieu RouleauLP2M, CNRS-UMR 7370, Faculty of Medicine, Nice, France.
Université Côte d'Azur · FRCentre National de la Recherche Scientifique · FRLaboratoire de PhysioMédecine Moléculaire · FRHôpital Saint Roch · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Despite mesenchymal stromal cells (MSCs) are considered as a promising source of cells to modulate immune functions on cells from innate and adaptive immune systems, their clinical use remains restricted (few number, limited

Indexed as

humanized NSG mousehuman T-cell immunosuppressioninduced pluripotent stem cellsmesenchymal stromal cellsregulatory T cellstolerance

Identifiers

PMID29422893
PMCPMC5788894
OpenAlexW2794126979

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.