ArticleFrontiers in physiology2018
Age-Related Vascular Changes Affect Turbulence in Aortic Blood Flow.
Article in Frontiers in physiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.
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Who cites it
34 citing papers in PubMed, 79 citations in OpenAlex.
- The influence of stenosis severity and geometric orientation on atherosclerotic progression: A fluid-structure interaction study in the carotid artery.Physical and engineering sciences in medicine · 2026Article
- From Hummingbird to Elephant: Amyloid Formation in Natural Transthyretin Variants.bioRxiv : the preprint server for biology · 2026Article
- FlowVN Trained on a Single Dataset Enables Rapid Reconstruction of Highly Accelerated 4D Flow MRI Across Multiple Sites.Magnetic resonance in medicine · 2026Article
- 4D Flow MRI Velocity and Turbulence Mapping in Mild Valvular Heart Disease.Journal of magnetic resonance imaging : JMRI · 2026Observational
- Preoperative Risk Stratification of Cerebral Infarction in Aortic Arch Surgery Using Quantitative Atheroma Assessment with Computational Fluid Dynamics.Annals of thoracic and cardiovascular surgery : official journal of the Association of Thoracic and Cardiovascular Surgeons of Asia · 2026Article
- Measurement of turbulent kinetic energy with colour Doppler echocardiography and particle tracing velocimetry in an ex-vivo aortic stenosis model.European heart journal. Imaging methods and practice · 2026Article
- 4D flow MRI enhances prototype testing of a total artificial heart.Scientific reports · 2025Article
- Evaluation of 4D Flow MRI-Derived Aortic Hemodynamics and Their Relationships With Left Ventricular Remodeling in Patients With Moderate Aortic Stenosis: A Preliminary Study.Echocardiography (Mount Kisco, N.Y.) · 2025Article
- A novel approach to flow visualization through mechanical heart valves.Proceedings of the Institution of Mechanical Engineers. Part H, Journal of engineering in medicine · 2025Article
- An in silico analysis of heart rate impact on wall shear stress hemodynamic parameters in aortic coarctation.Scientific reports · 2025Article
- Recommendations for defining disturbed flow as laminar, transitional, or turbulent in assays of hemostasis and thrombosis: communication from the ISTH SSC Subcommittee on Biorheology.Journal of thrombosis and haemostasis : JTH · 2025Review
- Changes of intracardiac flow dynamics measured by HyperDoppler in patients with aortic stenosis.European heart journal open · 2024Article
- Literature Survey for In-Vivo Reynolds and Womersley Numbers of Various Arteries and Implications for Compliant In-Vitro Modelling.Cardiovascular engineering and technology · 2024Review
- The Effect of Mechanical Circulatory Support on Blood Flow in the Ascending Aorta: A Combined Experimental and Computational Study.Bioengineering (Basel, Switzerland) · 2024Article
- In vitro investigation of the blood flow downstream of a 3D-printed aortic valve.Scientific reports · 2024Article
- Is fluid retention a cardiovascular risk factor?Clinical hemorheology and microcirculation · 2024Review
- Photoplethysmography for the Assessment of Arterial Stiffness.Sensors (Basel, Switzerland) · 2023Review
- Aortic growth after arch reconstruction with patch augmentation: a 2-decade experience.Interdisciplinary cardiovascular and thoracic surgery · 2023Article
- A clinician's guide to understanding aortic 4D flow MRI.Insights into imaging · 2023Review
- Aortic flow is associated with aging and exercise capacity.European heart journal open · 2023Article
Corrections and comments
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Authors and funding
9 authors at 1 institution in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Turbulent blood flow is implicated in the pathogenesis of several aortic diseases but the extent and degree of turbulent blood flow in the normal aorta is unknown. We aimed to quantify the extent and degree of turbulece in the normal aorta and to assess whether age impacts the degree of turbulence. 22 young normal males (23.7 ± 3.0 y.o.) and 20 old normal males (70.9 ± 3.5 y.o.) were examined using four dimensional flow magnetic resonance imaging (4D Flow MRI) to quantify the turbulent kinetic energy (TKE), a measure of the intensity of turbulence, in the aorta. All healthy subjects developed turbulent flow in the aorta, with total TKE of 3-19 mJ. The overall degree of turbulence in the entire aorta was similar between the groups, although the old subjects had about 73% more total TKE in the ascending aorta compared to the young subjects (young = 3.7 ± 1.8 mJ, old = 6.4 ± 2.4 mJ,
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.