Evidence map›Paper›PMID 29422840›Full record

ArticleFrontiers in neural circuits2018

Mechanisms Underlying Serotonergic Excitation of Callosal Projection Neurons in the Mouse Medial Prefrontal Cortex.

Emily K Stephens, Arielle L Baker, Allan T Gulledge

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in Frontiers in neural circuits, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Common and contrasting effects of 5-HTergic signaling in pyramidal cells and SOM interneurons of the mouse cortex.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2025
    Article
  6. Article
  7. Targeting 5-HTNeuroscience letters · 2022
    Article
  8. Article
  9. Article
  10. Article
  11. Frontiers in genetics · 2020
    Article
  12. Article
  13. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Emily K StephensDepartment of Molecular and Systems Biology, Geisel School of Medicine at Dartmouth College, Hanover, NH, United States.
Arielle L BakerDepartment of Molecular and Systems Biology, Geisel School of Medicine at Dartmouth College, Hanover, NH, United States.
Allan T GulledgeDepartment of Molecular and Systems Biology, Geisel School of Medicine at Dartmouth College, Hanover, NH, United States.
Dartmouth College · US

Funding

Neuromodulation of cortical circuits in health and diseaseR01MH099054 · NIMH · DARTMOUTH COLLEGE · PI GULLEDGE, ALLAN T · 2013 to 2017
$2.0M
NIMH NIH HHS R01 MH099054
6 · The paper itself

Abstract

Serotonin (5-HT) selectively excites subpopulations of pyramidal neurons in the neocortex via activation of 5-HT

Indexed as

AcetylcholineAnimalsCalciumCorpus CallosumFemaleKCNQ Potassium ChannelsMaleMembrane PotentialsMice, Inbred C57BLNeural PathwaysNeurotransmitter AgentsPrefrontal CortexPyramidal CellsReceptor, Serotonin, 5-HT2AReceptors, MuscarinicSerotoninAcetylcholineCalciumKCNQ Potassium ChannelsNeurotransmitter AgentsReceptor, Serotonin, 5-HT2AReceptors, MuscarinicSerotonin5-HT2A receptorafterdepolarizationcalciumcortexKv7 channelsM-currentpyramidal neuronserotonin

Identifiers

PMID29422840
PMCPMC5778113
OpenAlexW2790338938

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.