ArticlePostepy dermatologii i alergologii2017
Vitamin D status in recurrent aphthous stomatitis.
Article in Postepy dermatologii i alergologii, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed, 3 syntheses or guidelines pooled it, 42 citations in OpenAlex.
- Serum level of vitamin D in patients with recurrent aphthous stomatitis: A systematic review and meta-analysis of case control studies.Clinical and experimental dental research · 2024Pooled it
- Systematic review and meta-analysis of oxidative stress and antioxidant markers in recurrent aphthous stomatitis.BMC oral health · 2023Pooled it
- Vitamin D deficiency and risk of recurrent aphthous stomatitis: updated meta-analysis with trial sequential analysis.Frontiers in nutrition · 2023Pooled it
- Impact of zinc deficiency on the recurrence in aphthous stomatitis: A prospective case-control study.Bioinformation · 2026Article
- Optimization and preparation of a compound cod liver oil film former agent: an orthogonal design.Frontiers in pharmacology · 2024Article
- Psychological Functioning of Women Diagnosed with Lichen Planus and Other Diseases of the Oral Cavity-Explorative Study.Healthcare (Basel, Switzerland) · 2023Article
- Evaluation of Vitamin D Levels in Pediatric Patients With Recurrent Aphthous Stomatitis.Cureus · 2022Article
- Vitamin D and Its Role in Oral Diseases Development. Scoping Review.Dentistry journal · 2021Article
- Vitamin D and hematinic deficiencies in patients with recurrent aphthous stomatitis.Clinical oral investigations · 2020Article
- Chinese herbal medicine for recurrent aphthous stomatitis: a protocol for systematic review and meta-analysis.Medicine · 2018Article
- Vitamin D levels in patients with recurrent aphthous stomatitis.BMC oral health · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionRecurrent aphthous stomatitis (RAS) is a common chronic inflammatory oral mucosa disease with an unknown cause. However, dysregulation of the immune response seems to play an important role in this disease.
aimTo evaluate the vitamin D status in RAS patients and its effects on RAS severity, given the likely immunomodulatory function of vitamin D in the human organism. MATERIAL AND
methodsSixty-six patients with RAS and 66 controls were examined. Immunomodulatory or immunosuppressive treatment and other ulcerative oral diseases were used as exclusion criteria. The severity of RAS was assessed according to the clinical classification of the disease, the number of lesions per flare-up and the length of intervals between the attacks. The serum vitamin D level was established in each participant.
resultsThe mean serum vitamin D (25(OH)D) levels were found to be 16.81 ng/ml in the study group and 19.22 ng/ml in the control group, with no statistically significant difference between the two groups. In the study group, 5 (7.6%) participants were diagnosed with the "normal" vitamin D levels, while 16 (24.2%) had "insufficient" levels and 45 (68.2%) had "deficient" levels. The corresponding distribution in the control group was 8 (12.1%), 18 (27.3%) and 40 (60.6%), respectively. There was no statistical significance in the difference of vitamin D deficits between the study and the control groups. No correlation was detected between the severity of RAS and the serum vitamin D level.
conclusionsVitamin D does not seem to be a trigger factor for RAS occurrence and does not appear to influence the severity of the disease in the studied group.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.