Evidence map›Paper›PMID 29422818›Full record

ArticlePostepy dermatologii i alergologii2017

Circulating angiostatin serum level in patients with systemic sclerosis.

Zofia Gerlicz-Kowalczuk, Elzbieta Dziankowska-Zaborszczyk, Bożena Dziankowska-Bartkowiak

Open access · goldAbstract read
In one paragraph

Article in Postepy dermatologii i alergologii, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Zofia Gerlicz-KowalczukDepartment of Dermatology, Pediatric Dermatology and Dermatological Oncology, Lodz, Poland.
Elzbieta Dziankowska-ZaborszczykDepartment of Epidemiology and Biostatistics, the Chair of Social and Preventive Medicine of the Medical University of Lodz, Lodz, Poland.
Bożena Dziankowska-BartkowiakDepartment of Dermatology and Venereology, Medical University of Lodz, Lodz, Poland.
Medical University of Lodz · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionSystemic sclerosis (SSc) is achronic connective tissue disease characterized by microangiopathy with inadequate angiogenesis. Angiostatin (AS) is a potent antiangiogenic factor specifically inhibiting proliferation and inducing apoptosis of vascular endothelial cells.

aimTo evaluate the level of angiostatin in the serum of patients with SSc. MATERIAL AND

methodsSerum levels of AS were measured in 20 SSc patients and 12 healthy controls.

resultsA statistically significant difference in the serum levels of AS in SSc patients was observed compared to the control group (636.51 vs. 869.20 ng/ml;

conclusionsOur results reveal significant differences in AS level in SSc patients compared to the healthy controls, and suggest that a low level of AS may occur as a result of impaired angiogenesis.

Indexed as

angiogenesisangiostatinmicroangiopathysystemic sclerosis

Identifiers

PMID29422818
PMCPMC5799757
OpenAlexW2782223944

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.