Evidence map›Paper›PMID 29422815›Full record

ReviewPostepy dermatologii i alergologii2017

The role of regulatory T cells and genes involved in their differentiation in pathogenesis of selected inflammatory and neoplastic skin diseases. Part III: Polymorphisms of genes involved in Tregs' activation and function.

Bogusław Nedoszytko, Małgorzata Sokołowska-Wojdyło, Joanna Renke, Magdalena Lange, Piotr Trzonkowski, Michał Sobjanek, Aneta Szczerkowska-Dobosz, Marek Niedoszytko, Aleksandra Górska, Jan Romantowski and 3 more

Open access · goldAbstract readReview
In one paragraph

Review in Postepy dermatologii i alergologii, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.4field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Review
  3. Mastocytosis and Skin Cancer: The Current State of Knowledge.International journal of molecular sciences · 2023
    Review
  4. Review
  5. Article
  6. Article
  7. Genetic and Epigenetic Aspects of Atopic Dermatitis.International journal of molecular sciences · 2020
    Review
  8. Advances in Understanding the Immunological Pathways in Psoriasis.International journal of molecular sciences · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 1 institution in 1 country.

Bogusław NedoszytkoDepartment of Dermatology, Venereology and Allergology, Medical University of Gdansk, Gdansk, Poland.
Małgorzata Sokołowska-WojdyłoDepartment of Dermatology, Venereology and Allergology, Medical University of Gdansk, Gdansk, Poland.
Joanna RenkeDepartment of General and Medical Biochemistry, University of Gdansk, Gdansk, Poland.
Magdalena LangeDepartment of Dermatology, Venereology and Allergology, Medical University of Gdansk, Gdansk, Poland.
Piotr TrzonkowskiDepartment of Clinical Immunology and Transplantology, Medical University of Gdansk, Gdansk, Poland.
Michał SobjanekDepartment of Dermatology, Venereology and Allergology, Medical University of Gdansk, Gdansk, Poland.
Aneta Szczerkowska-DoboszDepartment of Dermatology, Venereology and Allergology, Medical University of Gdansk, Gdansk, Poland.
Marek NiedoszytkoDepartment of Allergology, Medical University of Gdansk, Gdansk, Poland.
Aleksandra GórskaDepartment of Pulmonology, Medical University of Gdansk, Gdansk, Poland.
Jan RomantowskiDepartment of Allergology, Medical University of Gdansk, Gdansk, Poland.
Jarosław SkokowskiDepartment of Oncological Surgery, Medical University of Gdansk, Gdansk, Poland.
Leszek KalinowskiDepartment of Medical Laboratory Diagnostic, Central Bank of Frozen Tissues and Genetic Specimens, Medical University of Gdansk, Gdansk, Poland.
Roman J NowickiDepartment of Dermatology, Venereology and Allergology, Medical University of Gdansk, Gdansk, Poland.
Gdańsk Medical University · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Regulatory T cells (Tregs) represent a cell type that promotes immune tolerance to autologous components and maintains immune system homeostasis. The abnormal function of Tregs is relevant to the pathogenesis of several skin diseases like psoriasis, atopic dermatitis, systemic lupus erythematosus, cutaneous T-cell lymphomas, and skin cancer and is also important in rheumatoid arthritis, diabetes and other autoimmune diseases. In this review, we will summarize the role of mutations and/or polymorphisms of genes involved in Tregs development, and functions in the pathogenesis of selected skin diseases.

Indexed as

skin diseasesTregs gene polymorphisms

Identifiers

PMID29422815
PMCPMC5799752
OpenAlexW2781692757

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.