ArticleIntestinal research2018
An analysis of dietary fiber and fecal fiber components including pH in rural Africans with colorectal cancer.
Article in Intestinal research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
7 citing papers in PubMed, 12 citations in OpenAlex.
- Article
- Perioperative Factors Affecting the Healing of Rectovaginal Fistula.Journal of clinical medicine · 2023Review
- Validating a semi-quantitative food frequency questionnaire to assess regional diet in a study of cancer in South West Nigeria.Cancer causes & control : CCC · 2023Article
- Evaluation of graded levels of corn-fermented protein on stool quality, apparent nutrient digestibility, and palatability in healthy adult cats.Journal of animal science · 2022Article
- Dietary Intake and Cancer in Sub-Saharan Africa: A Critical Review of Epidemiological Studies.Nutrition and cancer · 2022Review
- The colorectal cancer-associated faecal microbiome of developing countries resembles that of developed countries.Genome medicine · 2021Article
- Patterns of Early-Onset Colorectal Cancer Among Nigerians and African Americans.JCO global oncology · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
17 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND/
aimsColorectal cancer (CRC) is now a major public health problem with heavy morbidity and mortality in rural Africans despite the lingering dietary fiber-rich foodstuffs consumption. Studies have shown that increased intake of dietary fiber which contribute to low fecal pH and also influences the activity of intestinal microbiota, is associated with a lowered risk for CRC. However, whether or not the apparent high dietary fiber consumption by Africans do not longer protects against CRC risk is unknown. This study evaluated dietary fiber intake, fecal fiber components and pH levels in CRC patients.
methodsThirty-five subjects (CRC=21, control=14), mean age 45 years were recruited for the study. A truncated food frequency questionnaire and modified Goering and Van Soest procedures were used.
resultsWe found that all subjects consumed variety of dietary fiber-rich foodstuffs. There is slight preponderance in consumption of dietary fiber by the control group than the CRC patients. We also found a significant difference in the mean fecal neutral detergent fiber, acid detergent fiber, hemicellulose, cellulose and lignin contents from the CRC patients compared to the controls (
conclusionsThe identified differences in the fecal fiber components and stool pH levels between the 2 groups may relate to CRC incidence and mortality in rural Africans. There is crucial need for more hypothesis-driven research with adequate funding on the cumulative preventive role of dietary fiber-rich foodstuffs against colorectal cancer in rural Africans "today."
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Registered trials
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