Evidence map›Paper›PMID 29422767›Full record

ArticleMolecular vision2018

Acceleration of the formation of biofilms on contact lens surfaces in the presence of neutrophil-derived cellular debris is conserved across multiple genera.

Naiya B Patel, Jorge A Hinojosa, Meifang Zhu, Danielle M Robertson

Open access · greenAbstract read
In one paragraph

Article in Molecular vision, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.7field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 12 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Naiya B PatelDepartment of Ophthalmology, The University of Texas Southwestern Medical Center Dallas, TX.
Jorge A HinojosaDepartment of Ophthalmology, The University of Texas Southwestern Medical Center Dallas, TX.
Meifang ZhuDepartment of Ophthalmology, The University of Texas Southwestern Medical Center Dallas, TX.
Danielle M RobertsonDepartment of Ophthalmology, The University of Texas Southwestern Medical Center Dallas, TX.
The University of Texas Southwestern Medical Center · US

Funding

Effects of Systemic Disease on Corneal Epithelial PathophysiologyR01EY024546 · NEI · UT SOUTHWESTERN MEDICAL CENTER · PI DANIELLE M. ROBERTSON · 2015 to 2026
$4.3M
Outcome Measures for Clinical Trials in Pediatric Eye Care and StrabismusR01EY024333 · NEI · MAYO CLINIC ROCHESTER · PI FAUTSCH, MICHAEL P. · 2014 to 2018
$3.3M
Interactive effects of OSA and T2DM on corneal and ocular surface diseaseR21EY024433 · NEI · UT SOUTHWESTERN MEDICAL CENTER · PI ROBERTSON, DANIELLE M. · 2014 to 2015
$433k
NEI NIH HHS R01 EY024333NEI NIH HHS R01 EY024546NEI NIH HHS R21 EY024433
6 · The paper itself

Abstract

Purpose: We have previously shown that invasive strains of Methods: Five reference strains from the American Type Culture Collection were used: Results: Less than 1% of the starting inoculum adhered to the contact lens surface incubated with bacteria alone. There were no differences in adhesion rates to contact lens surfaces between bacteria in the absence of neutrophils for either the Gram-negative or Gram-positive test strains. Bacterial adhesion to contact lens surfaces was accelerated in the presence of human neutrophils for all test strains. This effect was least evident with Conclusions: These results show that in addition to

Indexed as

Bacterial AdhesionBiofilmsColony Count, MicrobialContact Lenses, HydrophilicCulture MediaExtracellular MatrixHumansMicrobial ViabilityMicroscopy, Electron, ScanningNeutrophilsPrimary Cell CulturePseudomonas aeruginosaSerratia marcescensStaphylococcus aureusStaphylococcus epidermidisStenotrophomonas maltophiliaCulture Media

Identifiers

PMID29422767
PMCPMC5800429
OpenAlexW2789634449

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.