Evidence map›Paper›PMID 29422752›Full record

ArticleMiddle East African journal of ophthalmology

Epidemiology and Clinical Features of Thyroid-associated Orbitopathy in Accra.

Edith Mawunyo Ackuaku-Dogbe, Josephine Akpalu, Benjamin Abaidoo

Abstract read
In one paragraph

Article in Middle East African journal of ophthalmology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  11. Graves' Orbitopathy: Report of 82 cases.La Tunisie medicale · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Edith Mawunyo Ackuaku-DogbeDepartment of Surgery, Eye Unit, School of Medicine and Dentistry, University of Ghana, Accra, Ghana.
Josephine AkpaluDepartment of Medicine and Therapeutics, School of Medicine and Dentistry, University of Ghana, Accra, Ghana.
Benjamin AbaidooDepartment of Surgery, Eye Unit, School of Medicine and Dentistry, University of Ghana, Accra, Ghana.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThyroid-associated orbitopathy (TAO), a clinical manifestation of Graves' disease, is an autoimmune disorder of the orbital and periorbital tissue. Data on the epidemiology and clinical presentation of TAO in Africa are generally scarce and unavailable in Ghana. We investigated the epidemiology and clinical features of TAO among patients with thyroid disorders attending the Korle Bu Teaching Hospital, Accra. SUBJECTS AND

methodsThis was a descriptive cross-sectional study of patients diagnosed with thyroid disorders which was conducted at the endocrine and orbital clinics of the Korle Bu Teaching Hospital. Diagnosis was based on clinical features and confirmed by a thyroid function test. Data collected and analyzed included demography, systemic and ocular features of thyroid disorder, and thyroid function tests.

resultsOf the 194 patients with thyroid disorders recruited, 117 (60.30%) had TAO. The mean age was 45.22 years (standard deviation: 13.90). The male:female ratio was 1:4.45. The most common ocular symptoms were "bulging eyes" (76/65.00%) and "puffy eyelid" (62/53.00%), and the common signs were eyelid retraction (97/82.91%) and proptosis (80/68.38%). Mild TAO was diagnosed in 64.96% of patients with only 6.84% having the severe form. The outcomes of the thyroid function test, thyroid disorder, and severity of TAO did not record any statistically significant differences.

conclusionsThe epidemiology is similar to those reported from other parts of the world, but the ocular presentation seems to be milder than in Caucasians.

Indexed as

AdultAge DistributionCross-Sectional StudiesFemaleGhanaGraves OphthalmopathyHospitals, TeachingHumansMaleMiddle AgedPrevalenceSex DistributionGoiterGraves' diseaseophthalmopathythyroidthyroid-associated orbitopathy

Identifiers

PMID29422752
PMCPMC5793449

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.