ArticleEuropean journal of human genetics : EJHG2018
Understanding the role of the chromosome 15q25.1 in COPD through epigenetics and transcriptomics.
Article in European journal of human genetics : EJHG, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it, 26 citations in OpenAlex.
- Different Associations Between theFrontiers in genetics · 2020Pooled it
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- A novel application of data-consistent inversion to overcome spurious inference in genome-wide association studies.Genetic epidemiology · 2024Article
- Mendelian randomization analysis identifies druggable genes and drugs repurposing for chronic obstructive pulmonary disease.Frontiers in cellular and infection microbiology · 2024Article
- De novo network analysis reveals autism causal genes and developmental links to co-occurring traits.Life science alliance · 2023Article
- Biological and Genetic Mechanisms of COPD, Its Diagnosis, Treatment, and Relationship with Lung Cancer.Biomedicines · 2023Review
- Genetic regulation of gene expression of MIF family members in lung tissue.Scientific reports · 2020Article
- Objectives, design and main findings until 2020 from the Rotterdam Study.European journal of epidemiology · 2020Article
- Transcriptome-wide association study reveals candidate causal genes for lung cancer.International journal of cancer · 2020Article
- Acetylcholine signaling system in progression of lung cancers.Pharmacology & therapeutics · 2019Review
- The etiologic origins for chronic obstructive pulmonary disease.International journal of chronic obstructive pulmonary disease · 2019Review
- Applying Functional Genomics to Chronic Obstructive Pulmonary Disease.Annals of the American Thoracic Society · 2018Review
Corrections and comments
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Authors and funding
21 authors at 9 institutions in 5 countries.
Funding
Abstract
Chronic obstructive pulmonary disease (COPD) is a major health burden in adults and cigarette smoking is considered the most important environmental risk factor of COPD. Chromosome 15q25.1 locus is associated with both COPD and smoking. Our study aims at understanding the mechanism underlying the association of chromosome 15q25.1 with COPD through epigenetic and transcriptional variation in a population-based setting. To assess if COPD-associated variants in 15q25.1 are methylation quantitative trait loci, epigenome-wide association analysis of four genetic variants, previously associated with COPD (P < 5 × 10
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Registered trials
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