ArticleScientific reports2018
Skeletal myosin binding protein-C isoforms regulate thin filament activity in a Ca
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Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.
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32citing papers in PubMed
4.1field-weighted citation impact, top 5% of its field
What it found
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Who cites it
32 citing papers in PubMed, 49 citations in OpenAlex.
- Fast skeletal myosin binding protein-C expression exacerbates dysfunction in heart failure.Basic research in cardiology · 2026Article
- Fast Myosin Binding Protein-C Is a Vital Regulator in Young and Aged Fast Skeletal Muscle Homeostasis.Journal of cachexia, sarcopenia and muscle · 2025Article
- The N-Terminal Mutations of cMyBP-C Affect Calcium Regulation, Kinetics, and Force of Muscle Contraction.International journal of molecular sciences · 2024Article
- Myosin-binding protein-H: Not just filler.The Journal of general physiology · 2024Review
- Functional role of myosin-binding protein H in thick filaments of developing vertebrate fast-twitch skeletal muscle.The Journal of general physiology · 2024Article
- Duality in disease: How two amino acid substitutions at actin residue 312 result in opposing forms of cardiomyopathy.The Journal of biological chemistry · 2024Article
- Non-Muscle Myosin II A: Friend or Foe in Cancer?International journal of molecular sciences · 2024Review
- Functional role of myosin-binding protein H in thick filaments of developing vertebrate fast-twitch skeletal muscle.bioRxiv : the preprint server for biology · 2024Article
- Etiology of genetic muscle disorders induced by mutations in fast and slow skeletal MyBP-C paralogs.Experimental & molecular medicine · 2023Review
- Regulation of cardiac function by cAMP nanodomains.Bioscience reports · 2023Review
- Fiber-Type Shifting in Sarcopenia of Old Age: Proteomic Profiling of the Contractile Apparatus of Skeletal Muscles.International journal of molecular sciences · 2023Review
- Single-molecule imaging reveals how mavacamten and PKA modulate ATP turnover in skeletal muscle myofibrils.The Journal of general physiology · 2023Article
- Cryo-Electron Microscopy Reveals Cardiac Myosin Binding Protein-C M-Domain Interactions with the Thin Filament.Journal of molecular biology · 2022Article
- Transcriptome Profile Identifies Actin as an Essential Regulator of Cardiac Myosin Binding Protein C3 Hypertrophic Cardiomyopathy in a Zebrafish Model.International journal of molecular sciences · 2022Article
- Myofilament glycation in diabetes reduces contractility by inhibiting tropomyosin movement, is rescued by cMyBPC domains.Journal of molecular and cellular cardiology · 2022Article
- Article
- Interaction of the C2 Ig-like Domain of Cardiac Myosin Binding Protein-C with F-actin.Journal of molecular biology · 2021Article
- Fast skeletal myosin-binding protein-C regulates fast skeletal muscle contraction.Proceedings of the National Academy of Sciences of the United States of America · 2021Article
- Diamond Nanofilm Normalizes Proliferation and Metabolism in Liver Cancer Cells.Nanotechnology, science and applications · 2021Article
- Influenza Infection has Fiber Type-Specific Effects on Cellular and Molecular Skeletal Muscle Function in Aged Mice.The journals of gerontology. Series A, Biological sciences and medical sciences · 2020Article
Corrections and comments
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Authors and funding
11 authors at 5 institutions in 3 countries.
Brian Leei LinDepartment of Cell and Molecular Physiology, Health Sciences Division, Loyola University Chicago, Maywood, IL, 60153, USA.
Amy LiDepartment of Molecular Physiology and Biophysics, University of Vermont, Burlington, VT, 05405, USA.
Ji Young MunDepartment of Cell and Developmental Biology, University of Massachusetts Medical School, Worcester, MA, 01655, USA.
Michael J PrevisDepartment of Molecular Physiology and Biophysics, University of Vermont, Burlington, VT, 05405, USA.
Samantha Beck PrevisDepartment of Molecular Physiology and Biophysics, University of Vermont, Burlington, VT, 05405, USA.
Stuart G CampbellDepartments of Biomedical Engineering and Cellular and Molecular Physiology, Yale University, New Haven, CT, 06520, USA.
Cristobal G Dos RemediosBosch Institute, Discipline of Anatomy and Histology, University of Sydney, Sydney, 2006, Australia.
Pieter de P TombeDepartment of Cell and Molecular Physiology, Health Sciences Division, Loyola University Chicago, Maywood, IL, 60153, USA.
Roger CraigDepartment of Cell and Developmental Biology, University of Massachusetts Medical School, Worcester, MA, 01655, USA.
David M WarshawDepartment of Molecular Physiology and Biophysics, University of Vermont, Burlington, VT, 05405, USA.
Sakthivel SadayappanDepartment of Cell and Molecular Physiology, Health Sciences Division, Loyola University Chicago, Maywood, IL, 60153, USA. sadayasl@ucmail.uc.edu.ORCID 0000-0003-2006-7678
University of Vermont · USLoyola University Chicago · USUniversity of Massachusetts Chan Medical School · USThe University of Sydney · AUYale University · US
Funding
Sarcomeric Modifications and Progressive Cardiac MaladaptationP01HL062426 · NHLBI · UNIVERSITY OF ILLINOIS AT CHICAGO · PI DE TOMBE, PIETER P. · 2000 to 2020
$42.4MVentricular and Cardiac Fiber Characterization and Integration CoreP01HL059408 · NHLBI · UNIVERSITY OF VERMONT &ST AGRIC COLLEGE · PI ROBBINS, JEFFREY · 1999 to 2014
$26.4MPATHOPHYSIOLOGY OF MYOCARDIAL DISEASEST32HL007227 · NHLBI · JOHNS HOPKINS UNIVERSITY · PI Chulan Kwon, WENDY S POST · 1985 to 2026
$21.2MFast myosin binding protein-C and cardiac contractility in heart failureR01HL105826 · NHLBI · UNIVERSITY OF CINCINNATI · PI SADAYAPPAN, SAKTHIVEL · 2011 to 2025
$4.5MSkeletal Myosin-Binding Protein C (MyBP-C): Molecular Structure and FunctionR01AR067279 · NIAMS · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI CRAIG, ROGER W, WARSHAW, DAVID M · 2015 to 2019
$2.3MCardiac Myosin-Binding Protein C: Molecular Modulation of Actomyosin Function.R01HL126909 · NHLBI · UNIVERSITY OF VERMONT & ST AGRIC COLLEGE · PI WARSHAW, DAVID M · 2015 to 2018
$1.9MMolecular mechanism of hypertrophic cardiomyopathy in populations of South Asian descendantsR01HL130356 · NHLBI · UNIVERSITY OF CINCINNATI · PI SADAYAPPAN, SAKTHIVEL · 2016 to 2019
$1.6MMolecular Modulation of Actomyosin Mechanics by Cardiac Myosin-Binding Protein CR00HL124041 · NHLBI · UNIVERSITY OF VERMONT & ST AGRIC COLLEGE · PI PREVIS, MICHAEL JOSEPH · 2016 to 2018
$747kProteomic approaches to validate novel cardiac biomarkers for myocardial infarctiK02HL114749 · NHLBI · UNIVERSITY OF CINCINNATI · PI SADAYAPPAN, SAKTHIVEL · 2012 to 2016
$498kMolecular Modulation of Actomyosin Mechanics by Cardiac Myosin-Binding Protein CK99HL124041 · NHLBI · UNIVERSITY OF VERMONT & ST AGRIC COLLEGE · PI PREVIS, MICHAEL JOSEPH · 2014 to 2015
$287kNHLBI NIH HHS K02 HL114749NHLBI NIH HHS K99 HL124041NHLBI NIH HHS P01 HL059408NHLBI NIH HHS P01 HL062426NHLBI NIH HHS R00 HL124041NHLBI NIH HHS R01 HL105826NHLBI NIH HHS R01 HL126909NHLBI NIH HHS R01 HL130356NHLBI NIH HHS T32 HL007227NIAMS NIH HHS R01 AR067279
Abstract
Muscle contraction, which is initiated by Ca
Indexed as
Myocardial ContractionMyocardiumActinsAnimalsCalciumCarrier ProteinsMaleMuscle ContractionMuscle, SkeletalMyosin Binding Protein CProtein IsoformsRats, Sprague-DawleyRecombinant ProteinsTropomyosinActinsCalciumCarrier ProteinsMyosin Binding Protein CProtein IsoformsRecombinant ProteinsTropomyosin
Identifiers
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Read underepoch 390
Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.