Evidence map›Paper›PMID 29422545›Full record

ArticleExperimental & molecular medicine2018

Silencing of peroxiredoxin II by promoter methylation is necessary for the survival and migration of gastric cancer cells.

Soo Hyun Hong, Chengchun Min, Yukyung Jun, Doo Jae Lee, Seung Hwa Kim, Joo Hyun Park, Jae Ho Cheong, Yoon Jung Park, Soo-Youl Kim, Sanghyuk Lee and 1 more

Open access · goldAbstract read
In one paragraph

Article in Experimental & molecular medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 15 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. PRDX2 plays an oncogenic role in esophageal squamous cell carcinoma via Wnt/β-catenin and AKT pathways.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2020
    Article
  5. Article
  6. The Role of Peroxiredoxin Family in Cancer Signaling.Journal of cancer prevention · 2019
    Review
  7. Review
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Soo Hyun HongDepartment of Life Sciences, Ewha Womans University, Seoul, Korea.
Chengchun MinDepartment of Life Sciences, Ewha Womans University, Seoul, Korea.
Yukyung JunDepartment of Life Sciences, Ewha Womans University, Seoul, Korea.
Doo Jae LeeDepartment of Life Sciences, Ewha Womans University, Seoul, Korea.
Seung Hwa KimDepartment of Surgery, Yonsei University College of Medicine, Seoul, Korea.
Joo Hyun ParkDepartment of Nutritional Science and Food Management, Ewha Womans University, Seoul, Korea.
Jae Ho CheongDepartment of Surgery, Yonsei University College of Medicine, Seoul, Korea.
Yoon Jung ParkDepartment of Nutritional Science and Food Management, Ewha Womans University, Seoul, Korea.
Soo-Youl KimDivision of Cancer Biology, Research Institute, National Cancer Center, Goyang, Korea.
Sanghyuk LeeDepartment of Life Sciences, Ewha Womans University, Seoul, Korea.
Sang Won KangDepartment of Life Sciences, Ewha Womans University, Seoul, Korea.
Ewha Womans University · KRNational Cancer Center · KRYonsei University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Peroxiredoxin (Prx), a family of ubiquitous thiol peroxidases, functions as a redox signaling regulator that controls cellular H

Indexed as

DNA MethylationGene SilencingPromoter Regions, GeneticBiomarkers, TumorCell Line, TumorCell MovementCell ProliferationCell SurvivalGene Expression Regulation, NeoplasticHumansHydrogen PeroxideKaplan-Meier EstimatePeroxiredoxinsPrognosisRNA, Small Interferingsrc-Family KinasesBiomarkers, TumorHydrogen PeroxidePeroxiredoxinsRNA, Small Interferingsrc-Family Kinases

Identifiers

PMID29422545
PMCPMC5903821
OpenAlexW2792476826

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.