ArticleDental materials : official publication of the Academy of Dental Materials2018
Evaluation of biofilm formation on novel copper-catalyzed azide-alkyne cycloaddition (CuAAC)-based resins for dental restoratives.
Article in Dental materials : official publication of the Academy of Dental Materials, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed.
- Review
- The Incorporation of Copper-Doped Bioactive Glass Nanoparticles into Resin Composites Improves Their Biological, Mechanical and Adhesive Properties.The journal of adhesive dentistry · 2025Article
- Current approaches to produce durable biomaterials: Trends in polymeric materials for restorative dentistry applications.Dental materials : official publication of the Academy of Dental Materials · 2024Review
- Triacrylamide-Based Adhesives Stabilize Bonds in Physiologic Conditions.Journal of dental research · 2022Article
- Metal Oxide Nanoparticles and Nanotubes: Ultrasmall Nanostructures to Engineer Antibacterial and Improved Dental Adhesives and Composites.Bioengineering (Basel, Switzerland) · 2021Review
- In situ activation of therapeutics through bioorthogonal catalysis.Advanced drug delivery reviews · 2021Review
- Copper Surfaces in Biofilm Control.Nanomaterials (Basel, Switzerland) · 2020Review
- Vinyl sulfonamide based thermosetting composites via thiol-Michael polymerization.Dental materials : official publication of the Academy of Dental Materials · 2020Article
- Toward dental caries: Exploring nanoparticle-based platforms and calcium phosphate compounds for dental restorative materials.Bioactive materials · 2019Review
- Biological and Mechanical Evaluation of Novel Prototype Dental Composites.Journal of dental research · 2019Article
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
objectiveFor the past several decades, the resins used in dental restorations have been plagued with numerous problems, including their implication in biofilm formation and secondary caries. The need for alternative resins is critical, and evaluation of biofilm formation on these resins is essential. The aim of this study was to evaluate in vitro biofilm formation on the surface of novel copper(I)-catalyzed azide-alkyne cycloaddition (CuAAC)-based resins and composites.
methodsCuAAC-based resins/composites made from varying azide monomers and different copper concentrations were compared with BisGMA-TEGDMA resins/composites that served as the control. Biofilms were formed using a mono-species model containing a luciferase-expressing strain of Streptococcus mutans. Luciferase activity was measured and the number of viable bacteria was enumerated on biofilms associated with each resin and composite.
resultsA significant reduction (p<0.05) in luciferase activity, and the number of viable bacteria recovered from biofilms on CuAAC-based resins and composites was observed in comparison to biofilms associated with the BisGMA-TEGDMA controls. SIGNIFICANCE: CuAAC-based resins do still allow for the formation of biofilms; however, the statistically significant reduction of growth that was associated with the CuAAC resin may enhance the longevity of restorations that incorporate CuAAC-based materials.
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