ArticleCancer imaging : the official publication of the International Cancer Imaging Society2018
Cement pulmonary embolism as a complication of percutaneous vertebroplasty in cancer patients.
Article in Cancer imaging : the official publication of the International Cancer Imaging Society, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.
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Who cites it
21 citing papers in PubMed, 1 synthesis or guideline pooled it, 43 citations in OpenAlex.
- Subsequent fractures after vertebroplasty in osteoporotic vertebral fractures: a meta-analysis.Neurosurgical review · 2022Pooled it
- Asymptomatic Multiple Bilateral Segmental Pulmonary Embolisms Caused by Cement After Multilevel Vertebroplasty: A Case Report and Literature Review.Case reports in surgery · 2026Article
- Simultaneous pulmonary and intracardiac bone cement embolism after vertebroplasty: a case report and literature review.Journal of cardiothoracic surgery · 2025Review
- Article
- Cement leakage into the paravertebral venous system and pulmonary cement embolism following percutaneous vertebroplasty: a case report.Frontiers in surgery · 2025Article
- Pulmonary embolism and intracardiac foreign bodies caused by bone cement leakage: a case report and literature review.Journal of cardiothoracic surgery · 2024Review
- An Incidental Finding of Pulmonary Cement Embolism Four Weeks After Vertebroplasty in a 50-Year-Old Man with Multiple Myeloma.The American journal of case reports · 2023Article
- Impact of Cytogenetic Abnormalities, Induction and Maintenance Regimens on Outcomes After High-Dose Chemotherapy and Autologous Stem Cell Transplantation in Patients With Newly Diagnosed Multiple Myeloma: A Decade-Long Real-World Experience.Journal of hematology · 2023Article
- Extensive Intracardiac Cement Embolism in a Patient Undergoing Workup for Bone Marrow Transplant.Journal of hematology · 2023Article
- A Novel Semi-Cannulated Screw Enhanced Bone Cement Augmentation and Pullout Strength in Posterior Cervical Lateral Mass Screw Fixations: An In Vitro Biomechanical and Morphological Study.Orthopaedic surgery · 2023Article
- Percutaneous pedicle screw fixation combined with percutaneous vertebroplasty for the treatment of thoracic and lumbar metastatic tumors.Journal of clinical and translational research · 2023Article
- CT features and risk factors of pulmonary cement embolism after vertebroplasty or kyphoplasty in patients with vertebral compression fracture: a retrospective cohort study.Quantitative imaging in medicine and surgery · 2023Article
- Risk factors for pulmonary cement embolism after percutaneous vertebroplasty and radiofrequency ablation for spinal metastases.Frontiers in oncology · 2023Article
- A retrospective cohort study on the efficacy and safety of percutaneous vertebroplasty combined with bone-filling mesh container in vertebral metastases with posterior wall defect.Frontiers in oncology · 2023Article
- Risk Factors for Pulmonary Cement Embolism (PCE) After Polymethylmethacrylate Augmentation: Analysis of 32 PCE Cases.Neurospine · 2021Article
- Efficacy and Safety of Balloon Kyphoplasty for Pathological Vertebral Fractures in Patients with Hematological Malignancies in Our Institution.Internal medicine (Tokyo, Japan) · 2021Article
- Clinical efficacy and safety of bone cement combined with radiofrequency ablation in the treatment of spinal metastases.BMC neurology · 2020Article
- Clinical characteristics and management of cardiac and/or pulmonary cement embolus after percutaneous vertebroplasty: a single center experience.Annals of translational medicine · 2019Article
- A modified wire-loop snare technique for the retrieval of a large cardiac cement embolus caused by cement leakage after percutaneous vertebroplasty.Journal of interventional medicine · 2019Article
- Pulmonary cement embolism following balloon kyphoplasty: The impact of a procedural complication in a new era for lung cancer management.Molecular and clinical oncology · 2019Article
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundVertebroplasty is a minimally invasive procedure commonly performed for vertebral compression fractures secondary to osteoporosis or malignancy. Leakage of bone cement into the paravertebral venous system and cement pulmonary embolism (cPE) are well described, mostly in patients with osteoporosis. Little is known about the clinical sequelae and outcomes in cancer patients. In this study, we report our experience with cPE following vertebroplasty performed in cancer patients.
methodsRecords of all consecutive cancer patients who underwent vertebroplasty at our institution were retrospectively reviewed. The procedure was performed via percutaneous injection of barium-opacified polymethyl-methacrylate cement.
resultsA total of 102 cancer patients with a median age of 53 (19-83) years were included. Seventy-eight (76.5%) patients had malignant vertebral fractures, and 24 (23.5%) patients had osteoporotic fractures. Cement PE was detected in 13 (12.7%) patients; 10 (76.9%) patients had malignant fractures, and the remaining three had osteoporotic fractures. Cement PE was mostly asymptomatic; however, 5 (38.5%) patients had respiratory symptoms that led to the diagnosis. Only the five symptomatic patients were anticoagulated. Cement PE was more common with multiple myeloma (MM); it occurred in 7 (18.9%) of the 37 patients with MM compared with only three (7.3%) of the 41 patients with other malignancies. No difference in incidence was observed between patients with osteoporotic or malignant vertebral fractures.
conclusionsCement PE is a relatively common complication following vertebroplasty and is mostly asymptomatic. Multiple myeloma is associated with the highest risk. Large-scale prospective studies can help identify risk factors and clinical outcomes and could lead to better prevention and therapeutic strategies.
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