ArticleBMC genomics2018
Lineage-specific duplications of NBS-LRR genes occurring before the divergence of six Fragaria species.
Article in BMC genomics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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15 citing papers in PubMed, 45 citations in OpenAlex.
- Evolutionary analysis of TIR- and non-TIR-NBS-LRR disease resistance genes in wild strawberries.Frontiers in plant science · 2024Article
- Trends in the evolution of intronless genes inFrontiers in plant science · 2023Article
- Evolution and functional analysis of the GRAS family genes in six Rosaceae species.BMC plant biology · 2022Article
- Chromosome-level genome assembly of Mentha longifolia L. reveals gene organization underlying disease resistance and essential oil traits.G3 (Bethesda, Md.) · 2022Article
- Genome-wide analysis of NBS-LRR genes in Rosaceae species reveals distinct evolutionary patterns.Frontiers in genetics · 2022Article
- Different scales of gene duplications occurring at different times have jointly shaped the NBS-LRR genes in Prunus species.Molecular genetics and genomics : MGG · 2022Article
- Genome-wide comparative analysis of the nucleotide-binding site-encoding genes in fourFrontiers in plant science · 2022Article
- The emergence and evolution of intron-poor and intronless genes in intron-rich plant gene families.The Plant journal : for cell and molecular biology · 2021Article
- Contrasting genetic variation and positive selection followed the divergence of NBS-encoding genes in Asian and European pears.BMC genomics · 2020Article
- Resistance Gene Analogs in the Brassicaceae: Identification, Characterization, Distribution, and Evolution.Plant physiology · 2020Article
- Ectopic Expression of Grapevine GeneInternational journal of molecular sciences · 2019Article
- Disease Resistance Genetics and Genomics in Octoploid Strawberry.G3 (Bethesda, Md.) · 2019Article
- Genome-Wide Characterization of NBS-Encoding Genes in Watermelon and Their Potential Association with Gummy Stem Blight Resistance.International journal of molecular sciences · 2019Article
- Genome- Wide Analysis of the Nucleotide Binding Site Leucine-Rich Repeat Genes of Four Orchids Revealed Extremely Low Numbers of Disease Resistance Genes.Frontiers in genetics · 2019Article
- Symbiotic incompatibility between soybean and Bradyrhizobium arises from one amino acid determinant in soybean Rj2 protein.PloS one · 2019Article
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3 authors at 3 institutions in 2 countries.
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Abstract
backgroundPlant disease resistance (R) genes are evolving rapidly and play a critical role in the innate immune system of plants. The nucleotide binding sites-leucine rich repeat (NBS-LRR) genes are one of the largest classes in plant R genes. Previous studies have focused on the NBS-LRR genes from one or several species of different genera, and the sequenced genomes of the genus Fragaria offer the opportunity to study the evolutionary processes of these R genes among the closely related species.
resultsIn this study, 325, 155, 190, 187, and 133 NBS-LRRs were discovered from F. x ananassa, F. iinumae, F. nipponica, F. nubicola, and F. orientalis, respectively. Together with the 144 NBS-LRR genes from F. vesca, a total of 1134 NBS-LRRs containing 866 multi-genes comprised 184 gene families across the six Fragaria genomes. Extremely short branch lengths and shallow nodes were widely present in the phylogenetic tree constructed with all of the NBS-LRR genes of the six strawberry species. The identities of the orthologous genes were highly significantly greater than those of the paralogous genes, while the Ks ratios of the former were very significantly lower than those of the latter in all of the NBS-LRR gene families. In addition, the Ks and Ka/Ks values of the TIR-NBS-LRR genes (TNLs) were significantly greater than those of the non-TIR-NBS-LRR genes (non-TNLs). Furthermore, the expression patterns of the NBS-LRR genes revealed that the same gene expressed differently under different genetic backgrounds in response to pathogens.
conclusionsThese results, combined with the shared hotspot regions of the duplicated NBS-LRRs on the chromosomes, indicated that the lineage-specific duplication of the NBS-LRR genes occurred before the divergence of the six Fragaria species. The Ks and Ka/Ks ratios suggested that the TNLs are more rapidly evolving and driven by stronger diversifying selective pressures than the non-TNLs.
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