Evidence map›Paper›PMID 29422032›Full record

ArticleBMC infectious diseases2018

Risk factors associated with cluster size of Mycobacterium tuberculosis (Mtb) of different RFLP lineages in Brazil.

Renata Lyrio Peres, Solange Alves Vinhas, Fabíola Karla Correa Ribeiro, Moisés Palaci, Thiago Nascimento do Prado, Bárbara Reis-Santos, Eliana Zandonade, Philip Noel Suffys, Jonathan E Golub, Lee W Riley and 1 more

Abstract read
In one paragraph

Article in BMC infectious diseases, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Genetic Diversity and Molecular Epidemiology ofThe American journal of tropical medicine and hygiene · 2019
    Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Renata Lyrio PeresNúcleo de Doenças Infecciosas, Universidade Federal do Espírito Santo, Vitória, Espirito Santo, Brazil.
Solange Alves VinhasNúcleo de Doenças Infecciosas, Universidade Federal do Espírito Santo, Vitória, Espirito Santo, Brazil.
Fabíola Karla Correa RibeiroNúcleo de Doenças Infecciosas, Universidade Federal do Espírito Santo, Vitória, Espirito Santo, Brazil.
Moisés PalaciNúcleo de Doenças Infecciosas, Universidade Federal do Espírito Santo, Vitória, Espirito Santo, Brazil.
Thiago Nascimento do PradoLaboratório de Epidemiologia da Universidade Federal do Espírito Santo, Av. Marechal Campos, 1468- Maruípe-, Vitória, ES, Brazil.
Bárbara Reis-SantosLaboratório de Epidemiologia da Universidade Federal do Espírito Santo, Av. Marechal Campos, 1468- Maruípe-, Vitória, ES, Brazil.
Eliana ZandonadeLaboratório de Epidemiologia da Universidade Federal do Espírito Santo, Av. Marechal Campos, 1468- Maruípe-, Vitória, ES, Brazil.
Philip Noel SuffysLaboratório de Biologia Molecular Aplicada a Micobactérias, Instituto Oswaldo Cruz - FioCruz, Rio de Janeiro, Brazil.
Jonathan E GolubSchool of Medicine, Johns Hopkins University, Baltimore, MD, USA.
Lee W RileyDivision of Infectious Disease and Vaccinology, School of Public Health, University of California, Berkeley, CA, USA.
Ethel Leonor MacielLaboratório de Epidemiologia da Universidade Federal do Espírito Santo, Av. Marechal Campos, 1468- Maruípe-, Vitória, ES, Brazil. ethel.maciel@gmail.com.

Funding

Innovative approaches for tuberculosis control in BrazilU2RTW006883 · FIC · FEDERAL UNIVERSITY OF RIO DE JANEIRO · PI LAPA E SILVA, JOSE ROBERTO · 2005 to 2015
$3.5M
FIC NIH HHS U2R TW006883
6 · The paper itself

Abstract

backgroundTuberculosis (TB) transmission is influenced by patient-related risk, environment and bacteriological factors. We determined the risk factors associated with cluster size of IS6110 RFLP based genotypes of Mycobacterium tuberculosis (Mtb) isolates from Vitoria, Espirito Santo, Brazil.

methodsCross-sectional study of new TB cases identified in the metropolitan area of Vitoria, Brazil between 2000 and 2010. Mtb isolates were genotyped by the IS6110 RFLP, spoligotyping and RD

resultsAmong 959 Mtb isolates, 461 (48%) cases had an isolate that belonged to an RFLP cluster, and six clusters with ten or more isolates were identified. Of the isolates spoligotyped, 448 (52%) were classified as LAM and 412 (48%) as non-LAM. Our regression model found that 6-9 isolates/RFLP cluster were more likely belong to the LAM family, having the RD

conclusionsWe found that a large proportion of new TB infections in Vitoria is caused by prevalent Mtb genotypes belonging to the LAM family and RD

Indexed as

Polymorphism, Restriction Fragment LengthAdultBrazilCitiesCross-Sectional StudiesFemaleGenotypeHumansMaleMiddle AgedMycobacterium tuberculosisPrevalenceRisk FactorsTuberculosisYoung AdultCluster sizeMolecular epidemiologyRisk factorsTransmissionTuberculosis

Identifiers

PMID29422032
PMCPMC5806441

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.