Evidence map›Paper›PMID 29421865›Full record

ArticleMolecular pharmaceutics2018

In Vitro Efficacy of Free and Nanoparticle Formulations of Gallium(III) meso-Tetraphenylporphyrine against Mycobacterium avium and Mycobacterium abscessus and Gallium Biodistribution in Mice.

Seoung-Ryoung Choi, Bradley E Britigan, Barbara Switzer, Traci Hoke, David Moran, Prabagaran Narayanasamy

Abstract read
In one paragraph

Article in Molecular pharmaceutics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.8field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 37 citations in OpenAlex.

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  5. International journal of molecular sciences · 2023
    Review
  6. Alternatives to Antibiotics againstAntibiotics (Basel, Switzerland) · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Seoung-Ryoung ChoiDepartment of Pathology and Microbiology, College of Medicine , University of Nebraska Medical Center , Omaha , Nebraska 68198 , United States.ORCID 0000-0003-4874-559X
Bradley E BritiganDepartment of Pathology and Microbiology, College of Medicine , University of Nebraska Medical Center , Omaha , Nebraska 68198 , United States.
Barbara SwitzerDepartment of Internal Medicine, College of Medicine , University of Nebraska Medical Center , Omaha , Nebraska 68198 , United States.
Traci HokeDepartment of Pathology and Microbiology, College of Medicine , University of Nebraska Medical Center , Omaha , Nebraska 68198 , United States.
David MoranDepartment of Pathology and Microbiology, College of Medicine , University of Nebraska Medical Center , Omaha , Nebraska 68198 , United States.
Prabagaran NarayanasamyDepartment of Pathology and Microbiology, College of Medicine , University of Nebraska Medical Center , Omaha , Nebraska 68198 , United States.ORCID 0000-0002-9617-5555
University of Nebraska Medical Center · USVA Nebraska Western Iowa Health Care System · US

Funding

Development of Gallium-Based Therapies for Pulmonary Mycobacterial InfectionsI01BX002504 · VA · OMAHA VA MEDICAL CENTER · PI BRITIGAN, BRADLEY E · 2015 to 2018
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Iron Acquisition by Mycobacterium tuberculosis Within PhagocytesI01CX000102 · VA · OMAHA VA MEDICAL CENTER · PI BRITIGAN, BRADLEY E · 2009 to 2013
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BLRD VA I01 BX002504CSRD VA I01 CX000102
6 · The paper itself

Abstract

The nontuberculous mycobacterial (NTM) pathogens, M. avium complex (MAC) and M. abscessus, can result in severe pulmonary infections. Current antibiotics confront significant challenges for treatment of these NTM infections due to emerging multidrug-resistance. Thus, development of new antibiotics targeted against these agents is needed. We examined the inhibitory activities of Ga(NO

Indexed as

AnimalsAnti-Bacterial AgentsCell Line, TumorFemaleGalliumHumansMiceMice, Inbred BALB CMicrobial Sensitivity TestsModels, AnimalMycobacterium abscessusMycobacterium aviumMycobacterium Infections, NontuberculousNanoparticlesPorphyrinsRespiratory Tract Infections5,10,15,20-tetraphenylporphyrinAnti-Bacterial AgentsGalliumgallium chloridePorphyrinsbiodistributiongallium nanoparticleMycobacterium abscessusMycobacterium aviumnontuberculous mycobacteria

Identifiers

PMID29421865
PMCPMC12136474
OpenAlexW2786913136

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.