Evidence map›Paper›PMID 29420701›Full record

ArticleCerebral cortex (New York, N.Y. : 1991)2019

Cerebellar Functional Connectivity in Term- and Very Preterm-Born Infants.

Charlotte S Herzmann, Abraham Z Snyder, Jeanette K Kenley, Cynthia E Rogers, Joshua S Shimony, Christopher D Smyser

Open access · bronzeAbstract read
In one paragraph

Article in Cerebral cortex (New York, N.Y. : 1991), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 42 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Review
  5. The Evolving Cerebellar and Cerebello-cortical Functional Connectivity Architecture during Infancy.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025
    Article
  6. Article
  7. Cerebellar Development and the Burden of Prematurity.Cerebellum (London, England) · 2025
    Review
  8. Review
  9. Article
  10. Temporal complexity of the BOLD-signal in preterm versus term infants.Cerebral cortex (New York, N.Y. : 1991) · 2024
    Article
  11. Article
  12. Functional parcellation of the neonatal cortical surface.Cerebral cortex (New York, N.Y. : 1991) · 2024
    Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Cerebellar Structure and Function in Autism Spectrum Disorder.Journal of psychiatry and brain science · 2022
    Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Charlotte S HerzmannDepartment of Neurology, Washington University School of Medicine, Saint Louis, MO, USA.
Abraham Z SnyderDepartment of Neurology, Washington University School of Medicine, Saint Louis, MO, USA.
Jeanette K KenleyDepartment of Neurology, Washington University School of Medicine, Saint Louis, MO, USA.
Cynthia E RogersDepartment of Psychiatry, Washington University School of Medicine, Saint Louis, MO, USA.
Joshua S ShimonyMallinckrodt Institute of Radiology, Washington University School of Medicine, Saint Louis, MO, USA.
Christopher D SmyserDepartment of Neurology, Washington University School of Medicine, Saint Louis, MO, USA.
Washington University in St. Louis · USMallinckrodt (United States) · US

Funding

WU INSTITUTE OF CLINICAL AND TRANSLATIONAL SCIENCESUL1TR002345 · NCATS · WASHINGTON UNIVERSITY · PI William G. Powderly · 2017 to 2026
$97.8M
Washington University Institute of Clinical and Translational SciencesUL1TR000448 · NCATS · WASHINGTON UNIVERSITY · PI EVANOFF, BRADLEY A · 2012 to 2016
$41.4M
Washington University Intellectual and Developmental Disabilities Research Center-Administrative Down Syndrome SupplementU54HD087011 · NICHD · WASHINGTON UNIVERSITY · PI CONSTANTINO, JOHN N. · 2015 to 2019
$7.1M
Trajectories of Cortico-Cerebellar Connectivity, Social Competence, and Internalizing Symptoms in Adolescents Born Very PretermR37MH113570 · NIMH · WASHINGTON UNIVERSITY · PI CYNTHIA Elise ROGERS, Christopher Daniel Smyser · 2022 to 2026
$3.8M
THE PRETERM BEHAVIORAL PHENOTYPE: TRAJECTORIES OF PSYCHOPATHOLOGY & CHANGES IN CEREBRAL CONNECTIVITYR01MH113570 · NIMH · WASHINGTON UNIVERSITY · PI ROGERS, CYNTHIA ELISE, SMYSER, CHRISTOPHER DANIEL · 2017 to 2021
$3.1M
UNDERSTANDING NEUROBEHAVIORAL DEFICITS IN PRETERM INFANTS THROUGH IMAGINGR01HD057098 · NICHD · WASHINGTON UNIVERSITY · PI INDER, TERRIE E, NEIL, JEFFREY J. · 2008 to 2012
$2.9M
PREDICTING FETAL ACIDEMIA WITH INTRAPARTUM ELECTRONIC FETAL HEART RATE MONITORINGR01HD061619 · NICHD · WASHINGTON UNIVERSITY · PI CAHILL, ALISON G, MACONES, GEORGE A · 2010 to 2014
$2.9M
NINDS CENTER CORE FOR BRAIN IMAGINGP30NS098577 · NINDS · WASHINGTON UNIVERSITY · PI RAICHLE, MARCUS E · 2016 to 2019
$2.4M
PREDICTING CHILDHOOD OUTCOMES IN PRETERM INFANTS USING CEREBRAL CONNECTIVITYK02NS089852 · NINDS · WASHINGTON UNIVERSITY · PI SMYSER, CHRISTOPHER DANIEL · 2014 to 2018
$848k
PREDICTING PRESCHOOL PSYCHOPATHOLOGY WITH BRAIN CONNECTIVITY IN PRETERM NEONATESK23MH105179 · NIMH · WASHINGTON UNIVERSITY · PI ROGERS, CYNTHIA ELISE · 2015 to 2018
$705k
NCATS NIH HHS UL1 TR000448NCATS NIH HHS UL1 TR002345NICHD NIH HHS R01 HD061619NICHD NIH HHS U54 HD087011NIMH NIH HHS K23 MH105179NIMH NIH HHS R01 MH113570NIMH NIH HHS R37 MH113570NINDS NIH HHS K02 NS089852NINDS NIH HHS P30 NS098577
6 · The paper itself

Abstract

Cortical resting state networks have been consistently identified in infants using resting state-functional connectivity magnetic resonance imaging (rs-fMRI). Comparable studies in adults have demonstrated cerebellar components of well-established cerebral networks. However, there has been limited investigation of early cerebellar functional connectivity. We acquired non-sedated rs-fMRI data in the first week of life in 57 healthy, term-born infants and at term-equivalent postmenstrual age in 20 very preterm infants (mean birth gestational age 27 ± 2 weeks) without significant cerebral or cerebellar injury. Seed correlation analyses were performed using regions of interests spanning the cortical and subcortical gray matter and cerebellum. Parallel analyses were performed using rs-fMRI data acquired in 100 healthy adults. Our results demonstrate that cortico-cerebellar functional connectivity is well-established by term. Intra- and cortico-cerebellar functional connectivity were largely similar in infants and adults. However, infants showed more functional connectivity structure within the cerebellum, including stronger homotopic correlations and more robust anterior-posterior anticorrelations. Prematurity was associated with reduced correlation magnitudes, but no alterations in intra- and cortico-cerebellar functional connectivity topography. These results add to the growing evidence that the cerebellum plays an important role in shaping early brain development during infancy.

Indexed as

BrainBrain MappingCerebellumFemaleGestational AgeHumansInfant, Extremely PrematureInfant, NewbornMagnetic Resonance ImagingMaleNeural Pathways

Identifiers

PMID29420701
PMCPMC6373668
OpenAlexW2791282668

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.