ArticleSexually transmitted diseases2018
Rapid Increase in Reports of Syphilis Associated With Men Who Have Sex With Women and Women Who Have Sex With Men, Japan, 2012 to 2016.
Article in Sexually transmitted diseases, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.
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32 citing papers in PubMed.
- Risk factors and diagnostic indicators for congenital syphilis: a Nationwide retrospective survey.Epidemiology and infection · 2025Article
- Syphilis in Pregnant Women and Congenital Syphilis in Japan, 2022 to 2023: A Warning for Other Countries.Sexually transmitted diseases · 2025Article
- Epidemic of multiple Treponema pallidum strains in men who have sex with men in Japan: efficient multi-locus sequence typing scheme and indicator biomarkers.AIDS research and therapy · 2024Article
- Influence of gender on clinical presentation, management practices and outcomes of ocular syphilis.Scientific reports · 2024Article
- Article
- Nephrotic "full-house" glomerulonephritis successfully treated with antibiotics alone in secondary syphilis: a case report.CEN case reports · 2024Article
- Temporal Trends in Syphilis Incidence among Men with HIV in Busan, Korea, 2005-2022: A Retrospective Cohort Study.Viruses · 2024Article
- Clinicopathologic assessment of secondary syphilis avoids misdiagnosis: results of comprehensive evaluation of 114 cases.Postepy dermatologii i alergologii · 2024Article
- A Rare Case of Blindness Caused by Syphilis with Malignant Hypertensive Nephropathy.Internal medicine (Tokyo, Japan) · 2023Article
- Secondary Syphilis Rash.JMA journal · 2023Article
- Examination of 93 cases of perianal warts and suggestion of a new classification.Annals of coloproctology · 2023Article
- Infectious syphilis in women and heterosexual men in major Australian cities: sentinel surveillance data, 2011-2019.The Medical journal of Australia · 2023Article
- Resurgence of syphilis in 2022 amongst heterosexual men and women in Osaka, Japan.Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases · 2023Article
- Article
- Concurrent coronavirus disease 2019 and primary syphilis in a young man: A rare case report.Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy · 2022Article
- Incidence Trends of Five Common Sexually Transmitted Infections Excluding HIV From 1990 to 2019 at the Global, Regional, and National Levels: Results From the Global Burden of Disease Study 2019.Frontiers in medicine · 2022Article
- Case Report: A Case Report of Neurosyphilis Mimicking Limbic Encephalitis.Frontiers in neurology · 2022Article
- Intra-urban differentials of congenital and acquired syphilis and syphilis in pregnant women in an urban area in northeastern Brazil.Transactions of the Royal Society of Tropical Medicine and Hygiene · 2021Article
- Hard bilateral syphilitic testes with vasculitis: a case report and literature review.BMC urology · 2021Review
- Phylogenetic and genetic characterization of Treponema pallidum strains from syphilis patients in Japan by whole-genome sequence analysis from global perspectives.Scientific reports · 2021Article
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10 authors.
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Abstract
backgroundIn Japan, syphilis reports have recently increased rapidly. However, unlike other developed countries where men who have sex with men (MSM) were associated with the rise, the increase in Japan has been attributed more to men who have sex with women (MSW) and women who have sex with men (WSM). We report on this increase based on surveillance data.
methodsSyphilis is a notifiable disease requiring all laboratory-confirmed cases to be reported; stage and sex of the sex partner(s) suspected as the infection source are also reported. Focusing on primary and secondary (P&S) cases, we describe the temporal, demographic, and geographic distributions of reported cases in 2012 through 2016.
resultsA total of 7040 (64.0%) of 10,997 cases were P&S; the annual rate of increase was greatest for P&S and the proportion of P&S increased over time. Among P&S cases (1609 MSM, 2768 MSW, and 1323 WSM), MSW and WSM each surpassed MSM cases in 2016. Men were older with a wider age distribution (median, 37 years; interquartile range, 28-46 years) relative to women (median, 26 years; interquartile range, 21-34 years). Among women, 20- to 24-year-olds consistently had the highest reporting rate, reaching 9.0 per 100,000 in 2016. Congenital syphilis reports increased from 0.4 in 2012 to 1.4 per 100,000 live births in 2016. Although Tokyo prefecture had the highest reporting rate (3.98 per 100,000 person-years), the proportionate contribution from Tokyo decreased in 2016.
conclusionsReports on P&S syphilis increased yearly among MSW and WSM. Young women seem to be at particular risk, and with increased reports of congenital syphilis, syphilis prevention and control is currently a public health priority in Japan.
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