Evidence map›Paper›PMID 29420068›Full record

ArticleAmerican journal of physiology. Gastrointestinal and liver physiology2018

VIP is involved in peripheral CRF-induced stimulation of propulsive colonic motor function and diarrhea in male rats.

Seiichi Yakabi, Lixin Wang, Hiroshi Karasawa, Pu-Qing Yuan, Kazuhiko Koike, Koji Yakabi, Yvette Taché

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in American journal of physiology. Gastrointestinal and liver physiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.7field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 17 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

Seiichi YakabiCURE: Digestive Diseases Research Center, Vatche and Tamar Manoukian Digestive Diseases Division, David Geffen School of Medicine, University of California, Los Angeles, and Veterans Affairs Greater Los Angeles Healthcare System, Los Angeles, California.
Lixin WangCURE: Digestive Diseases Research Center, Vatche and Tamar Manoukian Digestive Diseases Division, David Geffen School of Medicine, University of California, Los Angeles, and Veterans Affairs Greater Los Angeles Healthcare System, Los Angeles, California.
Hiroshi KarasawaCURE: Digestive Diseases Research Center, Vatche and Tamar Manoukian Digestive Diseases Division, David Geffen School of Medicine, University of California, Los Angeles, and Veterans Affairs Greater Los Angeles Healthcare System, Los Angeles, California.
Pu-Qing YuanCURE: Digestive Diseases Research Center, Vatche and Tamar Manoukian Digestive Diseases Division, David Geffen School of Medicine, University of California, Los Angeles, and Veterans Affairs Greater Los Angeles Healthcare System, Los Angeles, California.
Kazuhiko KoikeDepartment of Gastroenterology, Graduate School of Medicine, The University of Tokyo , Tokyo , Japan.
Koji YakabiDepartment of Gastroenterology and Hepatology, Saitama Medical Center, Saitama Medical University , Saitama , Japan.
Yvette TachéCURE: Digestive Diseases Research Center, Vatche and Tamar Manoukian Digestive Diseases Division, David Geffen School of Medicine, University of California, Los Angeles, and Veterans Affairs Greater Los Angeles Healthcare System, Los Angeles, California.
VA Greater Los Angeles Healthcare System · USUniversity of California, Los Angeles · USSaitama Medical University · JPThe University of Tokyo · JP

Funding

Pilot and Feasibility ProgramP30DK041301 · NIDDK · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI ROZENGURT, JUAN ENRIQUE · 1990 to 2019
$18.0M
Stress-Induced Activition of Colonic Motor FunctionR01DK057238 · NIDDK · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI TACHE, YVETTE FRANCE · 2000 to 2015
$3.3M
NIDDK NIH HHS P30 DK041301NIDDK NIH HHS R01 DK057238RRD VA I01 RX001685
6 · The paper itself

Abstract

We investigated whether vasoactive intestinal peptide (VIP) and/or prostaglandins contribute to peripheral corticotropin-releasing factor (CRF)-induced CRF

Indexed as

DiarrheaGastrointestinal MotilityMyenteric PlexusVasoactive Intestinal PeptideAnimalsColonCorticotropin-Releasing HormoneDefecationGenes, fosIleumIntestinal MucosaMaleNeuroprotective AgentsRatsCorticotropin-Releasing HormoneNeuroprotective AgentsVasoactive Intestinal Peptidec-Foscorticotropin-releasing factordiarrheaenteric neuronsvasoactive intestinal peptide antagonist

Identifiers

PMID29420068
PMCPMC6008061
OpenAlexW2787070121

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.