ArticleCancer2018
Fatigability and endurance performance in cancer survivors: Analyses from the Baltimore Longitudinal Study of Aging.
Article in Cancer, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
31 citing papers in PubMed, 44 citations in OpenAlex.
- Unveiling Factors Associated With Older Adult Accrual to Cancer Clinical Trials: Lessons From the ECOG-ACRIN Experience.Journal of the National Comprehensive Cancer Network : JNCCN · 2025Article
- Physical Health Decline After Chemotherapy or Endocrine Therapy in Breast Cancer Survivors.JAMA network open · 2025Article
- Diffuse large B-cell lymphoma presenting as acute lumbosacral plexopathy with persistent lower back pain and fatigability.Journal of family medicine and primary care · 2025Article
- Functional decline in older breast cancer survivors treated with and without chemotherapy and non-cancer controls: results from the Hurria Older PatiEnts (HOPE) prospective study.Journal of cancer survivorship : research and practice · 2024Observational
- Quality of Life, Physical Functioning, and Psychological Distress of Older Adults Undergoing Hematopoietic Stem Cell Transplantation.Transplantation and cellular therapy · 2023Article
- Design and methods of a translational, community-based, lifestyle weight management pilot intervention trial in breast cancer survivors with overweight or obesity.Contemporary clinical trials communications · 2023Article
- Measuring and Understanding the Health Impact of Greater Fatigability in Older Adults: A Call to Action and Opportunities.Fatigue : biomedicine, health & behavior · 2023Article
- Changes in Objectively Measured Physical Activity Are Associated With Perceived Physical and Mental Fatigability in Older Men.The journals of gerontology. Series A, Biological sciences and medical sciences · 2022Article
- Association of liver disease with brain volume loss, cognitive decline, and plasma neurodegenerative disease biomarkers.Neurobiology of aging · 2022Article
- Translation and linguistic validation of the Pittsburgh Fatigability Scale for Korean breast cancer survivors: A cognitive interviewing study.Cancer care research online · 2022Article
- Challenges of Survivorship for Older Adults Diagnosed with Cancer.Current oncology reports · 2022Review
- Article
- Functional decline among older cancer survivors in the Baltimore longitudinal study of aging.Journal of the American Geriatrics Society · 2021Article
- Accelerated aging in older cancer survivors.Journal of the American Geriatrics Society · 2021Article
- Traits and treadmills: Association between personality and perceived fatigability in well-functioning community-dwelling older adults.Psychology and aging · 2021Article
- Article
- Psychometric properties of the Korean version of the Pittsburgh Fatigability Scale in breast cancer survivors.Health and quality of life outcomes · 2021Article
- Fatigability as a Predictor of Subclinical and Clinical Anemia in Well-Functioning Older Adults.Journal of the American Geriatrics Society · 2020Article
- Epidemiology of Perceived Physical Fatigability in Older Adults: The Long Life Family Study.The journals of gerontology. Series A, Biological sciences and medical sciences · 2020Article
- Fatigability: A Prognostic Indicator of Phenotypic Aging.The journals of gerontology. Series A, Biological sciences and medical sciences · 2020Article
Corrections and comments
- Commented on by
Authors and funding
8 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundFatigue is prevalent and distressing among cancer survivors, but its subjective nature makes it difficult to identify. Fatigability, defined as task-specific fatigue, and endurance performance may be useful supplemental measures of functional status in cancer survivors.
methodsFatigability, endurance performance, and cancer history were assessed every 2 years in Baltimore Longitudinal Study of Aging participants between 2007 and 2015. Fatigability was defined according to the Borg rating of perceived exertion scale after a 5-minute, slow treadmill walk; and endurance performance was calculated according to the ability and time to complete a fast-paced, 400-meter walk. The association between cancer history, fatigability, and endurance performance was evaluated using longitudinal analyses adjusted for age, sex, body mass index, and comorbidities.
resultsOf 1665 participants, 334 (20%) reported a history of cancer. A combination of older age (>65 years) and a history of cancer was associated with 3.8 and 8.6 greater odds of high perceived fatigability and poor endurance, respectively (P < .01). Older adults with and without a history of cancer walked 42 and 23 seconds slower than younger adults without a history of cancer, respectively (P < .01). The median times to the development of high fatigability and poor endurance were shorter among those who had a history of cancer compared with those who had no history of cancer (P < .01).
conclusionsThe current findings suggest that a history of cancer is associated with fatigability and poor endurance and that this effect is significantly greater in older adults. Evaluating the effects of cancer and age on fatigability may illuminate potential pathways and targets for future interventions. Cancer 2018;124:1279-87. © 2018 American Cancer Society.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.