Evidence map›Paper›PMID 29419735›Full record

ArticleMolecules (Basel, Switzerland)2018

Bauerenol Acetate, the Pentacyclic Triterpenoid from Tabernaemontana longipes, is an Antitrypanosomal Agent.

Simira Carothers, Rogers Nyamwihura, Jasmine Collins, Huaisheng Zhang, HaJeung Park, William N Setzer, Ifedayo Victor Ogungbe

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Plant Terpenoids as Hit Compounds against Trypanosomiasis.Pharmaceuticals (Basel, Switzerland) · 2022
    Review
  3. Antimicrobial agents and chemotherapy · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Simira CarothersDepartment of Chemistry, Jackson State University, Jackson, MS 39217, USA. Simira.carothers@gmail.com.
Rogers NyamwihuraDepartment of Chemistry, Jackson State University, Jackson, MS 39217, USA. rogersnyamwihura@yahoo.com.
Jasmine CollinsDepartment of Chemistry, Jackson State University, Jackson, MS 39217, USA. Jcollins1908@gmail.com.
Huaisheng ZhangDepartment of Chemistry, Jackson State University, Jackson, MS 39217, USA. huiasheng.zhang@students.jsums.edu.
HaJeung ParkX-ray Crystallography Laboratory, Scripps Research Institute-FL, Jupiter, FL 33458, USA. hajpark@scripps.edu.
William N SetzerDepartment of Chemistry, University of Alabama in Huntsville, Huntsville, AL 35899, USA. wsetzer@chemistry.uah.edu.
Ifedayo Victor OgungbeDepartment of Chemistry, Jackson State University, Jackson, MS 39217, USA. ifedayo.v.ogungbe@jsums.edu.ORCID 0000-0002-8048-5137

Funding

RCMI-Center for Environmental HealthG12MD007581 · NIMHD · JACKSON STATE UNIVERSITY · PI TCHOUNWOU, PAUL B. · 2012 to 2017
$11.2M
Identification, Optimization and Structural Investigation of Antiprotozoal Agents and Molecular TargetSC3GM122629 · NIGMS · JACKSON STATE UNIVERSITY · PI OGUNGBE, IFEDAYO VICTOR · 2017 to 2020
$453k
Solution Structure and Novel Inhibitors of T. brucei Cathepsin LSC2GM109782 · NIGMS · JACKSON STATE UNIVERSITY · PI OGUNGBE, IFEDAYO VICTOR · 2014 to 2016
$412k
NIGMS NIH HHS SC2 GM109782NIGMS NIH HHS SC3 GM122629NIMHD NIH HHS G12 MD007581
6 · The paper itself

Abstract

The Latin American plant

Indexed as

Cell Line, TumorCell SurvivalHumansMagnetic Resonance SpectroscopyMolecular StructureParasitic Sensitivity TestsPlant ExtractsTabernaemontanaTriterpenesTrypanocidal AgentsTrypanosoma brucei bruceibauerenyl acetatePlant ExtractsTriterpenesTrypanocidal Agentspentacyclic triterpenoidTabernaemontana longipesTrypanosoma bruceitrypanosomiasis

Identifiers

PMID29419735
PMCPMC5911922

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.