ArticleJournal of glaucoma2018
Reduced Retinal Vessel Density in Primary Angle Closure Glaucoma: A Quantitative Study Using Optical Coherence Tomography Angiography.
Article in Journal of glaucoma, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
19 citing papers in PubMed, 46 citations in OpenAlex.
- Vessel Density and Structural Measurements in Primary Angle-Closure Suspect Glaucoma Using Optical Coherence Tomography Angiography.BioMed research international · 2020Trial
- Mid-term changes detected by corneal topography and optical coherence tomography after prophylactic laser iridotomy in primary angle closure suspect.International ophthalmology · 2026Article
- Plasma amino acid metabolic alterations and their associations with ocular parameters in early primary angle-closure glaucoma.Frontiers in medicine · 2026Article
- Applications of optical coherence tomography angiography in glaucoma: current status and future directions.Frontiers in medicine · 2024Review
- Parapapillary choroidal microvascular density in acute primary angle-closure and primary open-angle glaucoma: an optical coherence tomography angiography study.The British journal of ophthalmology · 2023Observational
- Quantitative Measurements of Vessel Density and Blood Flow Areas Primary Angle Closure Diseases: A Study of Optical Coherence Tomography Angiography.Journal of clinical medicine · 2022Article
- Assessment of the retinal vasculature in healthy Chinese preschool children aged 4-6 years old using optical coherence tomography angiography.BMC ophthalmology · 2021Article
- Comparison of optical coherence tomography angiography metrics in primary angle-closure glaucoma and normal-tension glaucoma.Scientific reports · 2021Article
- The vessel density of the superficial retinal capillary plexus as a new biomarker in cerebral small vessel disease: an optical coherence tomography angiography study.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2021Article
- Performance Assessment of Two Different Approaches of Measuring Skeletonized Radial Peripapillary Capillary Vessel Density in Glaucoma Patients.Frontiers in medicine · 2021Article
- Macular vessel density and foveal avascular zone parameters in patients after acute primary angle closure determined by OCT angiography.Scientific reports · 2020Article
- Optical coherence tomography angiography in glaucoma.Annals of translational medicine · 2020Review
- Optical Coherence Tomography Angiography in Glaucoma.Journal of glaucoma · 2020Review
- Optic Disc and Macular Vessel Density Measured by Optical Coherence Tomography Angiography in Open-Angle and Angle-Closure Glaucoma.Scientific reports · 2020Article
- Measurement of Retinal Changes in Primary Acute Angle Closure Glaucoma under Different Durations of Symptoms.Journal of ophthalmology · 2019Article
- Green Tea Extract Ameliorates Ischemia-Induced Retinal Ganglion Cell Degeneration in Rats.Oxidative medicine and cellular longevity · 2019Article
- Article
- Early Macular Angiography among Patients with Glaucoma, Ocular Hypertension, and Normal Subjects.Journal of ophthalmology · 2019Article
- Retinal Vascular Fingerprints as Novel Biomarkers for Primary Angle Closure Disease Progression.Ophthalmology scienceArticle
Corrections and comments
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Authors and funding
8 authors at 5 institutions in 3 countries.
Funding
Abstract
purposeThe purpose of this article is to investigate the changes in the retinal vasculature in different parts of the fundus in eyes with primary angle closure glaucoma (PACG).
methodsHealthy subjects and those with PACG were enrolled. Optical coherence tomography and a split-spectrum amplitude decorrelation angiography algorithm were used to quantify the retinal vessel densities in the parafoveal and peripapillary areas.
resultsThirty-nine eyes from 24 PACG patients and 39 eyes from 20 age-matched and sex-matched healthy subjects were included. The retinal vessel densities in the parafoveal and peripapillary areas and every sector of the 2 areas were significantly lower in the PACG eyes than in the healthy eyes. The difference was greater in the peripapillary area (11.75%) than in the parafoveal area (7.55%, P<0.05). In the PACG eyes, the vessel density in the peripapillary area correlated closely with the intraocular pressure, but that in the parafoveal area did not. When the PACG eyes were divided into groups with well-controlled and not well-controlled intraocular pressure (≤21 mm Hg or not), the vessel density and retinal nerve fiber layer thickness in the peripapillary area were much lower in the not well-controlled eyes (P<0.05), whereas the vessel density in the parafovea and the ganglion cell complex thickness were similar in the 2 subgroups.
conclusionRetinal vessel density was significantly reduced in PACG eyes. The magnitude of this difference varied between the fundus areas, and was greater in the peripapillary area.
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