ReviewNatural product reports2018
Total synthesis of complex terpenoids employing radical cascade processes.
Review in Natural product reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
38 citing papers in PubMed.
- Evolution of a Synthetic Strategy for Complex Diterpenes fromJournal of the American Chemical Society · 2026Article
- Synthesis of the Spirotetracyclic Core of the Ginkgolides via a Malonyl Radical Cascade.Organic letters · 2025Article
- Quaternary Carbon as a Locus for Skeletal Disconnection. Total Synthesis of (±)-Tubingensin A Featuring Assembly of the Backbone Stereotriad Using aJournal of the American Chemical Society · 2025Article
- A Dual Catalytic Approach for the Halogen-Bonding-Mediated Reductive Cleavage of α-Bromodifluoroesters and Amides.The Journal of organic chemistry · 2025Article
- Molecular complexity as a driving force for the advancement of organic synthesis.Nature reviews. Chemistry · 2024Review
- A Mechanistic Investigation of theThe Journal of organic chemistry · 2024Article
- Article
- Evidence of a Distinctive Enantioselective Binding Mode for the Photoinduced Radical Cyclization of α-Chloroamides in Ene-Reductases.ACS catalysis · 2023Article
- Enantioselective radical cascade cyclization via Ti-catalyzed redox relay.Tetrahedron letters · 2023Article
- Practical and General Alcohol Deoxygenation Protocol.Angewandte Chemie (International ed. in English) · 2023Article
- Combining the best of both worlds: radical-based divergent total synthesis.Beilstein journal of organic chemistry · 2023Review
- A Photoenzyme for Challenging Lactam Radical Cyclizations.Synlett : accounts and rapid communications in synthetic organic chemistry · 2022Article
- Convergent total synthesis of (+)-calcipotriol: A scalable, modular approach to vitamin D analogs.Proceedings of the National Academy of Sciences of the United States of America · 2022Article
- Total syntheses of strained polycyclic terpenes.Chemical communications (Cambridge, England) · 2022Review
- Stereoselective intermolecular radical cascade reactions of tryptophans or ɤ-alkenyl-α-amino acids with acrylamides via photoredox catalysis.Nature communications · 2022Article
- Bifunctional Polyene Cyclizations: Synthetic Studies on Pimarane Natural Products.Chemistry (Weinheim an der Bergstrasse, Germany) · 2021Article
- Controlling Enantioselectivity and Diastereoselectivity in Radical Cascade Cyclization for Construction of Bicyclic Structures.Journal of the American Chemical Society · 2021Article
- Deconjugative α-Alkylation of Cyclohexenecarboxaldehydes: An Access to Diverse Terpenoids.The Journal of organic chemistry · 2021Article
- Activation modes in biocatalytic radical cyclization reactions.Journal of industrial microbiology & biotechnology · 2021Review
- Reducing Challenges in Organic Synthesis with Stereoselective Hydrogenation and Tandem Catalysis.Journal of the American Chemical Society · 2021Article
Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
Covering: 2011-2017Radical cyclizations have a rich history in organic chemistry and have been particularly generous to the field of natural product synthesis. Owing to their ability to operate in highly congested molecular quarters, and with significant functional group compatibility, these transformations have enabled the synthesis of numerous polycyclic terpenoid natural products over the past several decades. Moreover, when programmed accordingly into a synthetic plan, radical cascade processes can be used to rapidly assemble molecular complexity, much in the same way nature rapidly constructs terpene frameworks through cationic cyclization pathways. This review highlights recent total syntheses of complex terpenoids (from 2011-2017) employing C-C bond-forming radical cascade sequences.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.