ArticleSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2018
Treatment toxicities and their impact on oral intake following non-surgical management for head and neck cancer: a 3-year longitudinal study.
Article in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Longitudinal Patterns of Radiation-Associated Dysphagia in Patients With Head and Neck Cancer: A Systematic Review.Head & neck · 2026Pooled it
- Taste disorder's management: a systematic review.Clinical oral investigations · 2020Pooled it
- EAT-10 Scores and Fiberoptic Endoscopic Evaluation of Swallowing in Head and Neck Cancer Patients.The Laryngoscope · 2021Trial
- Article
- Implementation of the "l'O à la bouche" Therapeutic Patient Education Program at a French Cancer Center: A Multidisciplinary Approach for Managing Post-Cancer Oral Toxicities.Journal of cancer education : the official journal of the American Association for Cancer Education · 2026Article
- An automatic pipeline for temporal monitoring of radiotherapy-induced toxicities in head and neck cancer patients.NPJ precision oncology · 2025Article
- Article
- Oral health-related quality of life after radiation therapy for head and neck cancer: the OraRad study.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2023Observational
- Screening oropharyngeal dysphagia in patients with head and neck cancer in a radiation oncology department.Reports of practical oncology and radiotherapy : journal of Greatpoland Cancer Center in Poznan and Polish Society of Radiation Oncology · 2023Article
- Post-acute health care needs of people with head and neck cancer: Mapping health care services, experiences, and the impact of rurality.Head & neck · 2022Article
- Lactoferrin supplementation for taste and smell abnormalities among patients receiving cancer chemotherapy.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2022Article
- Determinants of patient-reported xerostomia among long-term oropharyngeal cancer survivors.Cancer · 2021Article
- Clinical and sociodemographic factors that affect the quality of life of survivors of head and neck cancer.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2020Article
- The prevalence of patient-reported dysphagia and oral complications in cancer patients.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2020Article
- Optimising Radiation Therapy Dose to the Swallowing Organs at Risk: An In Silico Study of feasibility for Patients with Oropharyngeal Tumours.Dysphagia · 2019Article
- Article
- Content analysis of rehabilitation goals for patients following non-surgical head and neck cancer treatment.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2019Article
- Objective and subjective hyposalivation after treatment for head and neck cancer: Long-term outcomes.The Laryngoscope · 2018Article
- Pattern of dysphagia after swallowing-sparing intensity-modulated radiotherapy (IMRT) of head and neck cancers: results of a mono-institutional prospective study.Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposePatients who receive (chemo)radiotherapy [(C)RT] for head and neck cancer (HNC) experience multiple treatment effects. However, the presence and recovery of treatment toxicities and how these impact on oral intake over time post-treatment are not fully understood. The primary aim of this study was to examine patient perceptions of the toxicities present and which are barriers to oral intake, up to 3 years post (C)RT. The secondary aim was to identify mealtime strategies used to optimise oral intake.
methodsA prospective cohort of 96 patients after completion of (C)RT for HNC reported the presence of toxicities, if they were barriers to oral intake, and use of any mealtime strategies at the end of treatment (EoT), and at 3, 6, 12, 24, and 36 months post-treatment.
resultsAll toxicities and reported barriers changed over time (p < 0.05) except trismus. Odynophagia, reduced appetite, and fatigue improved (p < 0.05) by 3 months. Significantly less patients reported xerostomia and dysgeusia as barriers to oral intake at 3 months despite no improvement in their presence. No change in the presence of any toxicity or its impact on oral intake occurred from 12 to 36 months, with exception of dentition problems which significantly increased at 36 months. Alternating food/fluids was the most frequently used mealtime swallowing strategy at all time points beyond the EoT.
conclusionsThe dysphagia and associated toxicities HNC patients experience are chronic in nature. Rehabilitation should include mealtime strategies and support with adjusting to the changing presence and impact of toxicities on oral intake.
Indexed as
Identifiers
29417292What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.