Evidence map›Paper›PMID 29416914›Full record

ArticleJournal of pathology informatics2017

Routine Digital Pathology Workflow: The Catania Experience.

Filippo Fraggetta, Salvatore Garozzo, Gian Franco Zannoni, Liron Pantanowitz, Esther Diana Rossi

Open access · goldAbstract read
In one paragraph

Article in Journal of pathology informatics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 61 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
61citing papers in PubMed, 2 pooled it
5.4field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

61 citing papers in PubMed, 2 syntheses or guidelines pooled it, 105 citations in OpenAlex.

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  18. Digital pathology structure and deployment in Veneto: a proof-of-concept study.Virchows Archiv : an international journal of pathology · 2024
    Article
  19. Cutting-edge technology and automation in the pathology laboratory.Virchows Archiv : an international journal of pathology · 2024
    Review
  20. Article

1 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Filippo FraggettaPathology Unit, Cannizzaro Hospital, Catania, Italy.
Salvatore GarozzoPathology Unit, Cannizzaro Hospital, Catania, Italy.
Gian Franco ZannoniDivision of Anatomic Pathology and Histology, School of Medicine, "Agostino Gemelli", Rome, Italy.
Liron PantanowitzDepartment of Pathology, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA.
Esther Diana RossiDivision of Anatomic Pathology and Histology, School of Medicine, "Agostino Gemelli", Rome, Italy.
Agostino Gemelli University Polyclinic · ITOspedale Cannizzaro · ITUniversity of Pittsburgh Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionSuccessful implementation of whole slide imaging (WSI) for routine clinical practice has been accomplished in only a few pathology laboratories worldwide. We report the transition to an effective and complete digital surgical pathology workflow in the pathology laboratory at Cannizzaro Hospital in Catania, Italy.

methodsAll (100%) permanent histopathology glass slides were digitized at ×20 using Aperio AT2 scanners. Compatible stain and scanning slide racks were employed to streamline operations. eSlide Manager software was bidirectionally interfaced with the anatomic pathology laboratory information system. Virtual slide trays connected to the two-dimensional (2D) barcode tracking system allowed pathologists to confirm that they were correctly assigned slides and that all tissues on these glass slides were scanned.

resultsOver 115,000 glass slides were digitized with a scan fail rate of around 1%. Drying glass slides before scanning minimized them sticking to scanner racks. Implementation required introduction of a 2D barcode tracking system and modification of histology workflow processes.

conclusionOur experience indicates that effective adoption of WSI for primary diagnostic use was more dependent on optimizing preimaging variables and integration with the laboratory information system than on information technology infrastructure and ensuring pathologist buy-in. Implementation of digital pathology for routine practice not only leveraged the benefits of digital imaging but also creates an opportunity for establishing standardization of workflow processes in the pathology laboratory.

Indexed as

Digital pathologyinformaticspathologywhole slide imagingworkflow

Identifiers

PMID29416914
PMCPMC5760840
OpenAlexW2780025726

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.