Evidence map›Paper›PMID 29416875›Full record

ArticleThe journal of pathology. Clinical research2018

Patterns of BAP1 protein expression provide insights into prognostic significance and the biology of uveal melanoma.

Neil Farquhar, Sophie Thornton, Sarah E Coupland, Judy M Coulson, Joseph J Sacco, Yamini Krishna, Heinrich Heimann, Azzam Taktak, Colleen M Cebulla, Mohamed H Abdel-Rahman and 1 more

Open access · goldAbstract read
In one paragraph

Article in The journal of pathology. Clinical research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
47citing papers in PubMed, 1 pooled it
7.5field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

47 citing papers in PubMed, 1 synthesis or guideline pooled it, 73 citations in OpenAlex.

  1. Guideline
  2. Prognostic Impact of Concomitant Genomic Alterations in FGFR2-Positive Cholangiocarcinoma Treated With Pemigatinib.Liver international : official journal of the International Association for the Study of the Liver · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Role of miRNA in adult ocular tumorigenesis.Frontiers in molecular biosciences · 2025
    Review
  7. Article
  8. Review
  9. Review
  10. Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Vascular Lakes in Uveal Melanoma and Their Association With Outcome.Translational vision science & technology · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 2 countries.

Neil FarquharLiverpool Ocular Oncology Research Group, Department of Molecular and Clinical Cancer MedicineInstitute of Translational Medicine, University of LiverpoolLiverpoolUK.
Sophie ThorntonLiverpool Ocular Oncology Research Group, Department of Molecular and Clinical Cancer MedicineInstitute of Translational Medicine, University of LiverpoolLiverpoolUK.
Sarah E CouplandLiverpool Ocular Oncology Research Group, Department of Molecular and Clinical Cancer MedicineInstitute of Translational Medicine, University of LiverpoolLiverpoolUK.ORCID 0000-0002-1464-2069
Judy M CoulsonDepartment of Cellular and Molecular PhysiologyInstitute of Translational Medicine, University of LiverpoolLiverpoolUK.
Joseph J SaccoLiverpool Ocular Oncology Research Group, Department of Molecular and Clinical Cancer MedicineInstitute of Translational Medicine, University of LiverpoolLiverpoolUK.
Yamini KrishnaDepartment of Cellular PathologyRoyal Liverpool University HospitalLiverpoolUK.
Heinrich HeimannLiverpool Ocular Oncology Research Group, Department of Molecular and Clinical Cancer MedicineInstitute of Translational Medicine, University of LiverpoolLiverpoolUK.
Azzam TaktakLiverpool Ocular Oncology Research Group, Department of Molecular and Clinical Cancer MedicineInstitute of Translational Medicine, University of LiverpoolLiverpoolUK.
Colleen M CebullaDepartment of Ophthalmology and Visual ScienceHavener Eye Institute, The Ohio State UniversityColumbusOHUSA.
Mohamed H Abdel-RahmanDepartment of Ophthalmology and Visual ScienceHavener Eye Institute, The Ohio State UniversityColumbusOHUSA.ORCID 0000-0002-9493-7894
Helen KaliraiLiverpool Ocular Oncology Research Group, Department of Molecular and Clinical Cancer MedicineInstitute of Translational Medicine, University of LiverpoolLiverpoolUK.
University of Liverpool · GBThe Ohio State University · US

Funding

Translational Therapeutics Research Program (TT)P30CA016058 · NCI · OHIO STATE UNIVERSITY · PI Tasleem J Padamsee · 1985 to 2026
$132.3M
The Ohio State University Vision Sciences Research Core Program (OSU-VSRCP)P30EY032857 · NEI · OHIO STATE UNIVERSITY · PI Xiaoyi Raymond Gao · 2022 to 2026
$3.6M
Genetic polymorphisms in retinal detachment with proliferative vitreoretinopathyK08EY022672 · NEI · OHIO STATE UNIVERSITY · PI CEBULLA, COLLEEN MARIE · 2012 to 2016
$1.1M
Hereditary cancer predisposition syndromes and uveal melanomaR21CA191943 · NCI · OHIO STATE UNIVERSITY · PI ABDEL-RAHMAN, MOHAMED H. · 2015 to 2016
$368k
NCI NIH HHS P30 CA016058NCI NIH HHS R21 CA191943NEI NIH HHS K08 EY022672NEI NIH HHS P30 EY032857
6 · The paper itself

Abstract

Uveal melanoma (UM) is a rare aggressive intraocular tumour with a propensity for liver metastases, occurring in ∼50% of patients. The tumour suppressor

Indexed as

BAP1cytoplasmGolgiimmunohistochemistrymutationprognosisuveal melanoma

Identifiers

PMID29416875
PMCPMC5783957
OpenAlexW2789955711

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.