ArticleJournal of animal science and biotechnology2018
GLP1 and GIP are involved in the action of synbiotics in broiler chickens.
Article in Journal of animal science and biotechnology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 21 citations in OpenAlex.
- Effects of in ovo stimulation with potential epigenetic modulators on immune system phenotype across three generations in a chicken model.Scientific reports · 2025Article
- Modulatory effects of in ovo delivery of galactooligosaccharide and Lactiplantibacillus plantarum on antioxidant capacity, gene expression, and selected plasma metabolite parameters of broiler chickens.Journal of applied genetics · 2025Article
- Inter- and Transgenerational Effects of In Ovo Stimulation with Bioactive Compounds on Cecal Tonsils and Cecal Mucosa Transcriptomes in a Chicken Model.International journal of molecular sciences · 2025Article
- Low-Protein Diets Differentially Regulate Energy Balance during Thermoneutral and Heat Stress in Cobb Broiler Chicken (International journal of molecular sciences · 2024Article
- Physiological effects ofFrontiers in veterinary science · 2023Review
- Chicken embryo as a model in epigenetic research.Poultry science · 2021Review
- Effect of Fasting on the Spexin System in Broiler Chickens.Animals : an open access journal from MDPI · 2021Article
- The Effect of Hydrolyzed Insect Meals in Sea Trout Fingerling (Animals : an open access journal from MDPI · 2020Article
- Metabolic Gene Expression in the Muscle and Blood Parameters of Broiler Chickens Stimulated In Ovo with Synbiotics.Animals : an open access journal from MDPI · 2020Article
- Effect of synbiotics on thyroid hormones, intestinal histomorphology, and heat shock protein 70 expression in broiler chickens reared under cyclic heat stress.Poultry science · 2020Article
- Assessing the effect of starch digestion characteristics on ileal brake activation in broiler chickens.PloS one · 2020Article
- Modulation of microbial communities and mucosal gene expression in chicken intestines after galactooligosaccharides delivery In Ovo.PloS one · 2019Article
- Prebiotics and synbiotics - in ovo delivery for improved lifespan condition in chicken.BMC veterinary research · 2018Review
- Comparative study on the modulation of incretin and insulin homeostasis by butyrate in chicken and rabbit.PloS one · 2018Article
Corrections and comments
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Authors and funding
12 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundIn order to discover new strategies to replace antibiotics in the post-antibiotic era in meat-type chicken production, two new synbiotics were tested: (
methodsThe synbiotics were administered via syringe, using a special automatic system, into the egg air chamber of Cobb 500 broiler chicks on the 12
resultsSyn2 increased trypsin activity by 2.5-fold in the pancreas and 1.5-fold in the duodenal content. In the duodenum content, Syn2 resulted in ca 30% elevation in lipase activity and 70% reduction in amylase activity. Syn1 and Syn2 strongly decreased expression of mRNA for GLP-1 and GIP in the duodenum and for GLP-1 receptors in the pancreas. Simultaneously, concentrations of the incretins significantly diminished in the blood serum (
conclusionThe selected synbiotics may be used as in ovo additives for broiler chickens, and Syn2 seems to improve their potential digestive proteolytic and lipolytic ability. Our results suggest that synbiotics can be directly or indirectly involved in incretin secretion and reception.
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