Evidence map›Paper›PMID 29416817›Full record

ArticleOncotarget2018

Transplants of unrelated cord blood or sibling allogeneic peripheral blood stem cells/bone marrow in adolescent and young adults with chronic myeloid leukemia: comparable outcomes but better chronic GVHD-free and relapse-free survival among survivors with cord blood.

Changcheng Zheng, Xiaoyu Zhu, Baolin Tang, Xuhan Zhang, Lei Zhang, Liangquan Geng, Huilan Liu, Zimin Sun

Abstract read
In one paragraph

Article in Oncotarget, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. CML Chapter.Cancer treatment and research · 2021
    Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Changcheng ZhengDepartment of Hematology, Anhui Provincial Hospital, Anhui Medical University, Hefei, China.
Xiaoyu ZhuDepartment of Hematology, Anhui Provincial Hospital, Anhui Medical University, Hefei, China.
Baolin TangDepartment of Hematology, Anhui Provincial Hospital, Anhui Medical University, Hefei, China.
Xuhan ZhangDepartment of Hematology, Anhui Provincial Hospital, Anhui Medical University, Hefei, China.
Lei ZhangDepartment of Hematology, Anhui Provincial Hospital, Anhui Medical University, Hefei, China.
Liangquan GengDepartment of Hematology, Anhui Provincial Hospital, Anhui Medical University, Hefei, China.
Huilan LiuDepartment of Hematology, Anhui Provincial Hospital, Anhui Medical University, Hefei, China.
Zimin SunDepartment of Hematology, Anhui Provincial Hospital, Anhui Medical University, Hefei, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Adolescent and young adult (AYA) patients with hematological malignancy aged 15 to 39 years are recognized as a separate entity, and the efficacy and safety of unrelated cord blood transplantation (CBT) for chronic myeloid leukemia (CML) in AYA patients has not been reported. From March 2002 to June 2015, total of 106 CML patients received allogeneic hematopoietic cell transplantation (allo-HCT) in our center. Included in the present study were CML patients aged 15 to 39 years who received unrelated CBT or sibling allo-HCT, and 74 consecutive AYA patients with CML enrolled in this analysis. The day-100 cumulative incidences of grade 2-4 aGVHD and grade 3-4 aGVHD were similar following CBT and sibling-PBSCT/BMT. The cumulative incidences of cGVHD and extensive cGVHD were 21.7% and 5.3% in the CBT cohort, which were significantly lower than those in the sibling-PBSCT/BMT cohort (58.0% and 45.5%), respectively (

Indexed as

adolescent and young adultchronic GVHDchronic myeloid leukemiacord blood transplantationGVHD/relapse-free survival

Identifiers

PMID29416817
PMCPMC5788685

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.