Evidence map›Paper›PMID 29416735›Full record

ArticleOncotarget2018

Long non-coding RNA n326322 promotes the proliferation and invasion in nasopharyngeal carcinoma.

Mingyu Du, Teng Huang, Jing Wu, Jia-Jia Gu, Nan Zhang, Kai Ding, Lu-Xi Qian, Zhi-Wei Lu, Wen-Jun Zhang, Xiao-Kang Tian and 2 more

Abstract read
In one paragraph

Article in Oncotarget, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. MicroRNA-424-5p inhibits the proliferation, migration, and invasion of nasopharyngeal carcinoma cells by decreasing AKT3 expression.Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologica · 2020
    Article
  6. Article
  7. Article
  8. Long Noncoding RNA HOTTIP Promotes Nasopharyngeal Cancer Cell Proliferation, Migration, and Invasion by Inhibiting miR-4301.Medical science monitor : international medical journal of experimental and clinical research · 2019
    Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Mingyu Du *Xuzhou Medical University, Xuzhou, Jiangsu, China.
Teng Huang *Department of Radiation Oncology, Jiangsu Province Hospital of TCM, Nanjing, Jiangsu, China.
Jing WuJiangsu Cancer Hospital and Jiangsu Institue of Cancer Research and Nanjing Medical University Affiliated Cancer Hospital, Nanjing, Jiangsu, China.
Jia-Jia GuJiangsu Cancer Hospital and Jiangsu Institue of Cancer Research and Nanjing Medical University Affiliated Cancer Hospital, Nanjing, Jiangsu, China.
Nan ZhangJiangsu Cancer Hospital and Jiangsu Institue of Cancer Research and Nanjing Medical University Affiliated Cancer Hospital, Nanjing, Jiangsu, China.
Kai DingXuzhou Medical University, Xuzhou, Jiangsu, China.
Lu-Xi QianThe Fourth Clinical Medical College of Nanjing Medical University, Nanjing, Jiangsu, China.
Zhi-Wei LuThe Fourth Clinical Medical College of Nanjing Medical University, Nanjing, Jiangsu, China.
Wen-Jun ZhangThe Fourth Clinical Medical College of Nanjing Medical University, Nanjing, Jiangsu, China.
Xiao-Kang TianXuzhou Medical University, Xuzhou, Jiangsu, China.
Xia HeXuzhou Medical University, Xuzhou, Jiangsu, China.
Li YinJiangsu Cancer Hospital and Jiangsu Institue of Cancer Research and Nanjing Medical University Affiliated Cancer Hospital, Nanjing, Jiangsu, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Long non-coding RNAs (lncRNAs) have been reported to perform significant roles in cancer development and progression. Our research has found that a novel lncRNA n326322 was higher in nasopharyngeal carcinoma (NPC) cells. Moreover, the gain and loss of functional approaches revealed that the overexpression of lncRNA-n326322 promoted NPC cell proliferation and invasion, whereas the downregulation of lncRNA-n326322 suppressed cell proliferation and invasion. Further experiments demonstrated that potential mechanism may be associated with the activation of PI3K/AKT and ERK/MAPK pathways. Taken together, these results indicate that lncRNA-n326322 is associated with tumorigenesis of NPC.

Indexed as

invasionlncRNA-n326322nasopharyngeal carcinoma

Identifiers

PMID29416735
PMCPMC5788603

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.